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新生儿和儿童的真菌性心内膜炎

Fungal endocarditis in neonates and children.

作者信息

Millar B C, Jugo J, Moore J E

机构信息

Northern Ireland Public Health Laboratory, Department of Bacteriology, Belfast City Hospital, Lisburn Road, Belfast BT9 7AD, Northern Ireland, UK.

出版信息

Pediatr Cardiol. 2005 Sep-Oct;26(5):517-36. doi: 10.1007/s00246-004-0831-1.

Abstract

Fungal endocarditis in the neonate and pediatric population is associated with a high degree of morbidity and mortality, with diagnosis in the majority of cases made postmortem. The aim of this article is to review published literature on fungal endocarditis in children and to discuss the incidence due to a wide range of fungi, primarily Aspergillus and Candida species, as well as its diagnosis, including the importance of molecular-based approaches and various treatment regimes.

摘要

新生儿和儿童群体中的真菌性心内膜炎与高度的发病率和死亡率相关,大多数病例在死后才得以诊断。本文旨在回顾已发表的关于儿童真菌性心内膜炎的文献,并讨论由多种真菌(主要是曲霉菌和念珠菌属)引起的发病率,以及其诊断方法,包括基于分子的方法的重要性和各种治疗方案。

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