用于治疗注意缺陷多动障碍儿童的哌甲酯使用指南及算法
Guidelines and algorithms for the use of methylphenidate in children with Attention-Deficit/ Hyperactivity Disorder.
作者信息
Greenhill L, Beyer D H, Finkleson J, Shaffer D, Biederman J, Conners C K, Gillberg C, Huss M, Jensen P, Kennedy J L, Klein R, Rapoport J, Sagvolden T, Spencer T, Swanson J M, Volkow N
机构信息
New York State Psychiatric Institute/Columbia University, New York 10032, USA.
出版信息
J Atten Disord. 2002;6 Suppl 1:S89-100. doi: 10.1177/070674370200601s11.
OBJECTIVE
To review published algorithms for guiding the use of methylphenidate (MPH) in the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) in children and adolescents.
METHODS
A consensus roundtable of 12 experts was convened to review the evidence for the safety and efficacy of MPH in the treatment of ADHD, as well as the published algorithms and practice guidelines for using MPH. The experts reviewed the algorithms for practicality and acceptability by clinicians.
RESULTS
Algorithms that included MPH commonly selected it as the initial medication to be employed in the treatment of children with ADHD. Factors involved included its high efficacy, good safety record, and the ubiquitous nature of its appearance in the ADHD treatment literature.
CONCLUSIONS
MPH should be considered as the first medication to be used in a treatment algorithm for children and adolescents with ADHD.
目的
回顾已发表的关于指导使用哌甲酯（MPH）治疗儿童和青少年注意力缺陷多动障碍（ADHD）的算法。
方法
召集了一个由12名专家组成的共识圆桌会议，以审查MPH治疗ADHD的安全性和有效性证据，以及已发表的使用MPH的算法和实践指南。专家们审查了这些算法对临床医生的实用性和可接受性。
结果
包含MPH的算法通常将其选为治疗ADHD儿童的初始用药。涉及的因素包括其高效性、良好的安全记录以及在ADHD治疗文献中普遍出现的性质。
结论
MPH应被视为治疗儿童和青少年ADHD的算法中首先使用的药物。
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