Paterson A H, Peckham M J, McCready V R
Br Med J. 1976 May 8;1(6018):1118-21. doi: 10.1136/bmj.1.6018.1118.
Whole-body scanning using gallium-67-citrate gave consistently accurate tumour localisation in patients with seminoma of the testis. Thirteen out of 15 scans performed in patients with disseminated seminoma in relapse gave good imaging in all disease areas. Scans in patients with teratoma of the testis were less consistently positive; of nine scans performed in patients with disseminated teratoma seven were entirely negative and two scans lightly imaged large disease masses in two patients. In eight patients with combined (seminoma and teratoma) tumours the scan seemed to reflect the dominant tumour type at the time of scanning. In one of these patients the scans changed from positive to negative, being positive when seminoma was the dominant tumour and negative when a teratoma developed. Gallium-67-citrate scanning is useful in managing seminoma of the testis, both for determining the extent of disease present at initial presentation and for routine follow-up. It may be useful in the differential diagnosis of combined tumours when tumour masses are greater than 2 cm in diameter.
使用枸橼酸镓-67进行全身扫描，在睾丸精原细胞瘤患者中能始终如一地准确实现肿瘤定位。在复发的播散性精原细胞瘤患者所进行的15次扫描中，有13次在所有疾病区域均获得了良好的成像效果。睾丸畸胎瘤患者的扫描结果阳性率较低；在播散性畸胎瘤患者所进行的9次扫描中，7次完全为阴性，2次仅轻度显示了2例患者的较大病灶。在8例混合性（精原细胞瘤和畸胎瘤）肿瘤患者中，扫描结果似乎反映了扫描时占主导的肿瘤类型。其中1例患者的扫描结果从阳性变为阴性，当精原细胞瘤占主导时为阳性，而当畸胎瘤出现时则为阴性。枸橼酸镓-67扫描对于睾丸精原细胞瘤的管理很有用，既有助于确定初诊时疾病的范围，也有助于进行常规随访。当肿瘤肿块直径大于2 cm时，它可能有助于混合性肿瘤的鉴别诊断。
