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脑电图介导的亚急性硬化性全脑炎异常表现的诊断

EEG-mediated diagnosis of an unusual presentation of SSPE.

作者信息

Dunand A C, Jallon P

机构信息

Epilepsy and EEG Unit, University Hospital, 1211 14, Geneva, Switzerland.

出版信息

Clin Neurophysiol. 2003 Apr;114(4):737-9. doi: 10.1016/s1388-2457(02)00306-1.

DOI:10.1016/s1388-2457(02)00306-1
PMID:12686281
Abstract

OBJECTIVE

To highlight the role of EEG in the diagnosis of SSPE.

METHODS

EEG was performed in an 18 month old girl who had a 1 week history of repeated episodes of sudden flexion of the head and trunk and frequent falls.

RESULTS

EEG abnormalities consisted of stereotyped, generalized and synchronous high amplitude periodic complexes. These abnormalities correlated with brief episodes of axial and upper limb atonia on electromyogram examination. They persisted during sleep although abnormal movements disappeared. Biological results and cerebral MRI confirmed the diagnosis of subacute sclerosing panencephalitis.

CONCLUSIONS

This case is exceptional because of the age of the patient, the clinical presentation and the mode of contamination and it highlights the role of EEG in this diagnosis.

摘要

目的

强调脑电图(EEG)在亚急性硬化性全脑炎(SSPE)诊断中的作用。

方法

对一名18个月大的女童进行了脑电图检查,该女童有1周反复出现头部和躯干突然屈曲发作及频繁跌倒的病史。

结果

脑电图异常表现为刻板、广泛性和同步性高幅周期性复合波。这些异常与肌电图检查中短暂的轴性和上肢肌张力缺失发作相关。尽管异常运动消失,但在睡眠期间这些异常持续存在。生物学检查结果和脑部磁共振成像(MRI)证实了亚急性硬化性全脑炎的诊断。

结论

该病例因患者年龄、临床表现和感染方式而具有特殊性,它凸显了脑电图在这一诊断中的作用。

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