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利用尿液聚合酶链反应确定性病门诊男性患者阴道毛滴虫的患病率及临床表现。

Use of urine polymerase chain reaction to define the prevalence and clinical presentation of Trichomonas vaginalis in men attending an STD clinic.

作者信息

Wendel K A, Erbelding E J, Gaydos C A, Rompalo A M

机构信息

Division of Infectious Diseases, Oklahoma University Health Science Center, Oklahoma, USA.

出版信息

Sex Transm Infect. 2003 Apr;79(2):151-3. doi: 10.1136/sti.79.2.151.

DOI:10.1136/sti.79.2.151
PMID:12690140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1744621/
Abstract

OBJECTIVE

To determine the prevalence and clinical features of Trichomonas vaginalis (TV) infection in men.

METHODS

Men attending a public STD clinic in Baltimore, Maryland, were evaluated between March and July 2000. Clinicians recorded a standardised history and clinical examination. Urethral swab specimens were collected for Gram stain and Neisseria gonorrhoeae culture. First fraction urine samples were evaluated with TV culture and chlamydia and TV polymerase chain reaction (PCR). True positive TV was defined as a positive TV culture or a positive TV PCR confirmed with a second primer set.

RESULTS

355 men were evaluated in 363 visits. The prevalence of gonorrhoea, TV, and chlamydia were 19%, 13%, and 11%, respectively. In men over 28 years, the prevalence of TV was significantly higher than chlamydia. Age and urethritis by Gram stain were associated with a positive result on TV culture (p=0.03 and p=0.02, respectively) but not associated with TV infection as defined by a positive TV culture or a confirmed TV PCR. Discharge or dysuria was reported in 47% and 22% of men with TV, respectively.

CONCLUSIONS

TV prevalence in an urban STD clinic setting was high. Older age and urethritis were not significantly associated with TV infection as defined by a positive TV culture or a confirmed TV PCR.

摘要

目的

确定男性阴道毛滴虫(TV)感染的患病率及临床特征。

方法

2000年3月至7月对马里兰州巴尔的摩一家公立性传播疾病诊所的男性患者进行评估。临床医生记录标准化病史并进行临床检查。采集尿道拭子标本进行革兰氏染色及淋病奈瑟菌培养。收集首段尿标本进行TV培养以及衣原体和TV聚合酶链反应(PCR)检测。真正的TV阳性定义为TV培养阳性或用第二套引物证实的TV PCR阳性。

结果

共对355名男性进行了363次就诊评估。淋病、TV和衣原体的患病率分别为19%、13%和11%。在28岁以上男性中,TV的患病率显著高于衣原体。年龄和革兰氏染色显示的尿道炎与TV培养阳性结果相关(p分别为0.03和0.02),但与TV培养阳性或经证实的TV PCR定义的TV感染无关。TV阳性男性中分别有47%和22%报告有分泌物或排尿困难。

结论

在城市性传播疾病诊所环境中TV患病率较高。年龄较大和尿道炎与TV培养阳性或经证实的TV PCR定义的TV感染无显著相关性。

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