Khatib N, Bradbury C, Chalker V, Koh G C K W, Smit E, Wilson S, Watson J
Heart of England Foundation Trust, Heartlands Hospital, Birmingham, UK
Heart of England Foundation Trust, Heartlands Hospital, Birmingham, UK.
Int J STD AIDS. 2015 May;26(6):388-92. doi: 10.1177/0956462414539464. Epub 2014 Jun 12.
We conducted a study to determine the prevalence of Trichomonas vaginalis (TV), Mycoplasma genitalium (MG) and Ureaplasma urealyticum (UU) in men with urethritis, attending an urban sexual health clinic, in order to inform screening and treatment policies. Men attending an urban sexual health clinic between June 2011 and January 2012 were evaluated. Urine samples were collected from men with urethritis and tested for Chlamydia trachomatis (CT), Neisseria gonorrhoeae (GC) and TV using transcription-mediated amplification and for MG and UU using polymerase chain reaction. Eighty-three samples were analysed. The prevalence of CT was 33.7% (28/83), GC was 16.8% (14/83), TV was 3.6% (3/83), MG was 12.0% (10/83) and UU was 4.8% (4/83). Fifteen men had recurrent urethritis. Of these, three were found to have had TV, five to have had MG and none to have had UU, at initial presentation. Given the prevalence of MG in this study, there is an urgent need for further larger studies looking at optimal treatment regimens and screening strategies in urethritis.
我们开展了一项研究，以确定在一家城市性健康诊所就诊的尿道炎男性患者中阴道毛滴虫（TV）、生殖支原体（MG）和解脲脲原体（UU）的感染率，从而为筛查和治疗政策提供依据。对2011年6月至2012年1月期间在一家城市性健康诊所就诊的男性进行了评估。从尿道炎男性患者中采集尿液样本，采用转录介导扩增法检测沙眼衣原体（CT）、淋病奈瑟菌（GC）和TV，采用聚合酶链反应检测MG和UU。共分析了83份样本。CT感染率为33.7%（28/83），GC为16.8%（14/83），TV为3.6%（3/83），MG为12.0%（10/83），UU为4.8%（4/83）。15名男性患有复发性尿道炎。其中，初次就诊时，3人被发现感染TV，5人感染MG，无人感染UU。鉴于本研究中MG的感染率，迫切需要进一步开展更大规模的研究，以探讨尿道炎的最佳治疗方案和筛查策略。
