Varga Péter Pál
Semmelweis Egyetem, Ortopédiai Klinika, Budapest.
Ideggyogy Sz. 2003 Jan 20;56(1-2):20-7.
Chordoma is an uncommon malignant tumor with unusual characteristics developing in the remnants of the notochord and usually manifesting itself in patients in their forties and fifties. It is usually located in the body's symmetrical axis or attached to it. The pathological structure is rather characteristic to benign tumors. Although not painful, it is a mercilessly aggressive local tumor, in some cases resulting metastatic progression and might alter its histological picture in long-lived patients. It is found most prevalently (about 60 percent) in the sacrococcygeal region and at the clivus and manifesting itself spinally (over the sacrum) most likely in the lumbar region. Between 1992 and 2002, the authors have treated surgically 37 patients with sacrococcygeal chordoma. They applied wide resection following which only seven patients required re-operation. They show detailed data regarding this patient group and discuss the technical aspects of the wide tumor-resection.
脊索瘤是一种罕见的恶性肿瘤,具有不寻常的特征,发生于脊索残余部位,通常在四五十岁的患者中出现。它通常位于身体的对称轴上或附着于该轴。其病理结构具有相当典型的良性肿瘤特征。虽然不痛,但它是一种极具侵袭性的局部肿瘤,在某些情况下会发生转移进展,并且在长期存活的患者中可能会改变其组织学表现。它最常见于(约60%)骶尾区域和斜坡,最有可能在腰椎区域沿脊柱(在骶骨上方)表现出来。1992年至2002年期间,作者对37例骶尾脊索瘤患者进行了手术治疗。他们采用了广泛切除,术后只有7例患者需要再次手术。他们展示了关于该患者群体的详细数据,并讨论了广泛肿瘤切除的技术方面。