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经皮导管冷冻消融治疗房室结折返性心动过速:一种新消融技术的疗效与安全性

Percutaneous catheter cryothermal ablation of atrioventricular nodal reentrant tachycardia: efficacy and safety of a new ablation technique.

作者信息

Riccardi Riccardo, Gaita Fiorenzo, Caponi Domenico, Grossi Stefano, Scaglione Marco, Caruzzo Enrico, Di Donna Paolo, Pistis Gianfranco, Richiardi Elena, Giustetto Carla, Bocchiardo Mario

机构信息

Division of Cardiology, Mauriziano Hospital, Largo Turati, 62, 10126 Torino.

出版信息

Ital Heart J. 2003 Jan;4(1):35-43.

Abstract

BACKGROUND

Radiofrequency catheter ablation is nowadays a widely used technique for the treatment of arrhythmias; however, due to the possible complications such as atrioventricular block when radiofrequency is delivered in the septal area, this type of energy is not optimal. In contrast, cryoenergy has several positive features; first of all, it allows for the creation of reversible lesions and hence to test the effects of the ablation while the lesion is still forming thus reducing the number of ineffective and useless lesions. In addition, it also allows for the evaluation of the acute effects on the structures adjacent to the ablation site. The aim of the present study was to analyze the effectiveness and safety of catheter cryoablation in the treatment of atrioventricular nodal reentrant tachycardia (AVNRT).

METHODS

Thirty-two patients presenting with AVNRT underwent catheter cryoablation using a 7F catheter. When the optimal parameters were recorded, "ice mapping" at -30 degrees C was performed for 80 s to validate the ablation site by means of a reversible lesion. If the expected result was achieved, the cryoablation was carried out lowering the temperature to -75 degrees C for 4 min thus creating a permanent lesion.

RESULTS

Slow pathway ablation guided by a slow pathway potential was successfully performed in 31 out of the 32 patients with a mean of 2.6 +/- 1.0 cryoapplications. No complications occurred in any patients. Transient AH prolongation was observed in 2 patients in a midseptal site during the ice mapping phase of AVNRT ablation.

CONCLUSIONS

Cryoablation is a safe and effective technique for AVNRT ablation. It may be useful particularly when the ablation must be performed close to the atrioventricular node or His bundle, due to the possibility of validating the site of ablation by means of ice mapping that creates only a reversible lesion.

摘要

背景

射频导管消融术是目前治疗心律失常广泛应用的技术;然而,由于在间隔区域进行射频消融时可能出现诸如房室传导阻滞等并发症,这种能量类型并非最佳选择。相比之下,冷冻能量有几个积极特性;首先,它能形成可逆性损伤,从而在损伤仍在形成时测试消融效果,减少无效和无用损伤的数量。此外,它还能评估对消融部位相邻结构的急性影响。本研究的目的是分析导管冷冻消融治疗房室结折返性心动过速(AVNRT)的有效性和安全性。

方法

32例AVNRT患者使用7F导管进行导管冷冻消融。记录到最佳参数后,在-30℃进行80秒的“冰标测”,通过可逆性损伤来验证消融部位。如果达到预期结果,则将温度降至-75℃进行4分钟的冷冻消融,从而形成永久性损伤。

结果

32例患者中有31例在慢径电位引导下成功进行了慢径消融,平均冷冻消融2.6±1.0次。所有患者均未发生并发症。在AVNRT消融的冰标测阶段,2例位于中隔部位的患者出现短暂AH间期延长。

结论

冷冻消融是一种安全有效的AVNRT消融技术。特别是当消融必须在靠近房室结或希氏束处进行时,它可能很有用,因为可以通过仅产生可逆性损伤的冰标测来验证消融部位。

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