右旋苯丙胺对精神运动技能的影响。

Effects of dextroamphetamine on psychomotor skills.

作者信息

Evans M A, Martz R, Lemberger L, Rodda B E, Forney R B

出版信息

Clin Pharmacol Ther. 1976 Jun;19(6):777-81. doi: 10.1002/cpt1976196777.

DOI:10.1002/cpt1976196777

Abstract

Twelve healthy male volunteers were given 0, 5, 10, 15 mg/70 kg dextroamphetamine orally in a randomized double-blind fashion. Blood pressure increased linearly with dose while heart rate was unchanged. Although selected individual tests of stance stability and motor function improved in a dose-related fashion, a generalized improvement in performance was not found. Delayed Auditory Feedback (DAF) failed to show improvement in mental performance after dextroamphetamine.

摘要

12名健康男性志愿者以随机双盲方式口服0、5、10、15毫克/70千克右旋苯丙胺。血压随剂量呈线性升高，而心率未变。虽然所选的姿势稳定性和运动功能的个别测试呈剂量相关改善，但未发现整体表现有所改善。右旋苯丙胺后，延迟听觉反馈（DAF）未能显示出心理表现的改善。