Gupta P K, Lichstein E, Chadda K D
Chest. 1976 May;69(5):599-604. doi: 10.1378/chest.69.5.599.
Heart block was noted in 60 (35 complete and 25 second-degree) of 410 patients with acute inferior wall myocardial infarction. This group with heart block was compared to a control group of 30 patients with acute inferior wall infarction without heart block. The incidences of prior myocardial infarction and hypertension, in addition to the highest level of serum creatine phosphokinase and a maximum degree of ST-segment elevation in the inferior leads, were all greater in patients with heart block, as compared to the controls. The incidences of various complications, including dizziness and syncope, transient hypotension, cardiogenic shock, and congestive heart failure, were also higher in the group with heart block, while sinus nodal distrubances and atrial arrhythmias occurred with equal frequency. The mortality in those with heart block was 28 percent compared to 13 percent for the control. It is concluded that patients with heart block complicating acute inferior myocardial infarction have a greater amount of myocardial necrosis, a higher incidence of complications, and a higher mortality. Insertion of a temporary pacemaker should be considered when specific indications are present and not routinely.
在410例急性下壁心肌梗死患者中,有60例(35例完全性和25例二度)出现心脏传导阻滞。将这组有心脏传导阻滞的患者与30例无心脏传导阻滞的急性下壁梗死患者组成的对照组进行比较。与对照组相比,有心脏传导阻滞的患者既往心肌梗死和高血压的发生率、血清肌酸磷酸激酶的最高水平以及下壁导联ST段抬高的最大程度均更高。包括头晕和晕厥、短暂性低血压、心源性休克和充血性心力衰竭在内的各种并发症的发生率在有心脏传导阻滞的组中也更高,而窦房结紊乱和房性心律失常的发生率相同。有心脏传导阻滞患者的死亡率为28%,而对照组为13%。结论是,并发急性下壁心肌梗死的心脏传导阻滞患者有更多的心肌坏死、更高的并发症发生率和更高的死亡率。当有特定指征时应考虑插入临时起搏器,而非常规进行。