Jowett N I, Thompson D R, Pohl J E
Coronary Care Unit, Leicester General Hospital, UK.
Postgrad Med J. 1989 Apr;65(762):211-5. doi: 10.1136/pgmj.65.762.211.
The role of temporary percutaneous endocardial pacing has been examined in a retrospective analysis of all paced patients admitted to one coronary care unit over a 6 year period. The majority of 162 cases (84.6%) were paced for complete heart block complicating acute myocardial infarction. These patients had a higher incidence of previous hypertension, myocardial infarction and diabetes, compared to matched controls (P less than 0.05, less than 0.02 and less than 0.001, respectively). Admission blood glucose levels were also higher (P less than 0.05). The in-hospital mortality was high (46.7%), especially for those with anterior myocardial infarction (74.5%). Twenty-five (15.4%) patients without recent myocardial infarction were paced for symptomatic brady-dysrhythmias, usually due to chronic complete heart block (Lenegre's disease) or sick sinus syndrome. Most later required permanent pacing. Complications of temporary pacing were more frequent in those who died, the most common being dysrhythmias during pacemaker insertion. Review of our cases suggests that whilst facilities for temporary pacing were extremely valuable, many cases treated were not haemodynamically compromised and probably did not require pacing. Guidelines should be established on coronary care units to prevent the unnecessary morbidity, mortality and expense of the procedure.
在一项对一家冠心病监护病房6年期间收治的所有起搏患者的回顾性分析中,研究了临时经皮心内膜起搏的作用。162例患者中的大多数(84.6%)因急性心肌梗死并发完全性心脏传导阻滞而接受起搏治疗。与匹配的对照组相比,这些患者既往高血压、心肌梗死和糖尿病的发生率更高(P分别小于0.05、小于0.02和小于0.001)。入院时血糖水平也更高(P小于0.05)。住院死亡率很高(46.7%),尤其是前壁心肌梗死患者(74.5%)。25例(15.4%)近期无心肌梗死的患者因有症状的缓慢性心律失常接受起搏治疗,通常是由于慢性完全性心脏传导阻滞(勒内格雷病)或病态窦房结综合征。大多数患者后来需要永久性起搏。临时起搏的并发症在死亡患者中更常见,最常见的是起搏器插入期间的心律失常。对我们病例的回顾表明,虽然临时起搏设备非常有价值,但许多接受治疗的患者并无血流动力学受损,可能并不需要起搏。应在冠心病监护病房制定指导方针,以防止该操作带来不必要的发病率、死亡率和费用。