Radionuclide angiocardiographic measurement of left ventricular volume and ejection fraction.

In recent years a number of different radionuclidic techniques have been developed to measure left ventricular volume and ejection fraction. Area-measurement concepts have been applied to static and electrocardiographically gated radionuclidic images which have resulted in accurate measurement of left ventricular end-diastolic volume (LVEDV) and ejection fraction (LVEF). Gated (end-diastolic and end-systolic) image analysis has also proven capable of detecting regional left ventricular wallmotion abnormalities in patients with coronary disease. Time-activity curves can be extracted from left ventricular images, and several dynamic techniques have been developed and have also resulted in accurate measurement of LVEDV and LVEF. Radionuclide methods are currently available which are accurate and atraumatic and consequently applicable to the serial study of patients with heart disease. In particular, several of these radionuclide methods are relatively inexpensive and should be able to be performed in most hospitals.