Beitzke A, Müller W D, Becker H
Rofo. 1975 Sep;123(3):242-6. doi: 10.1055/s-0029-1230188.
Three cases of severe costovertebral deformities together with embryologically related cardiac malformations (Fallots Tetralogy and Truncus arteriosus communis) are presented. Two patients died because of their thoracic deformities and limited respiratory function. Relationships to similar bizarre veretebral anomalies are discussed. The cause is probably a teratogenic agent, acting between the fifth to eight embryologic week.
本文报告了3例严重的肋椎畸形病例,这些病例伴有胚胎学相关的心脏畸形(法洛四联症和共同动脉干)。两名患者因胸廓畸形和呼吸功能受限而死亡。文中讨论了与类似奇异椎体异常的关系。病因可能是一种致畸剂,在胚胎发育的第5至8周起作用。