Kim Baek-Nam, Kim Nam Joong, Kim Mi-Na, Kim Yang Soo, Woo Jun-Hee, Ryu Jiso
Division of Infectious Diseases, Keimyung University Dongsan Medical Center, Daegu, Korea.
Scand J Infect Dis. 2003;35(2):98-103. doi: 10.1080/0036554021000027015.
To characterize the clinical features of bacteraemia due to tribe Proteeae, 132 cases among 130 patients from 1991 to 2000 were analysed. The organisms included the Proteus species in 63 cases (P. mirabilis in 41, P. penneri in 2 and P. vulgaris in 20), the Providencia species in 8 (P. rettgeri in 3 and P. stuartii 5) and Morganella morganii in 61. Morganella bacteraemia occurred more frequently in the hospital (70.5%). Biliary and hepatic diseases were predominant in cases with Morganella bacteraemia while cardiovascular, urological and neurological diseases were more common in cases with Proteus bacteraemia. Biliary drainage catheters had more frequently been placed in cases with Morganella bacteraemia (39.3%, p < 0.001), and urinary catheters more frequently in cases with Proteus bacteraemia (17.5%). Biliary infection was most common in cases with Morganella bacteraemia (49.2%), while urinary tract infection (UTI) was most common in cases with Proteus bacteraemia (47.6%). Mortality directly related to bacteraemia due to tribe Proteeae was 20.8% (22.6, 50.0 and 15.0% for Proteus, Providencia and Morganella bacteraemia, respectively). In conclusion, Morganella bacteraemia was most frequently associated with biliary infection, while Proteus bacteraemia was most frequently with UTI. Providencia bacteraemia was relatively uncommon and it can be associated with infections other than UTI.
为了描述变形杆菌族所致菌血症的临床特征，对1991年至2000年间130例患者中的132例病例进行了分析。分离出的菌株包括63例变形杆菌属（奇异变形杆菌41例、彭氏变形杆菌2例、普通变形杆菌20例）、8例普罗威登斯菌属（雷氏普罗威登斯菌3例、斯氏普罗威登斯菌5例）和61例摩根摩根菌。摩根菌血症在医院内发生更为频繁（70.5%）。摩根菌血症患者以胆道和肝脏疾病为主，而变形杆菌菌血症患者中心血管、泌尿和神经系统疾病更为常见。摩根菌血症患者更常留置胆道引流导管（39.3%，p<0.001），变形杆菌菌血症患者更常留置导尿管（17.5%）。摩根菌血症患者中胆道感染最为常见（49.2%），而变形杆菌菌血症患者中尿路感染（UTI）最为常见（47.6%）。变形杆菌族所致菌血症直接相关的死亡率为20.8%（变形杆菌、普罗威登斯菌和摩根菌菌血症的死亡率分别为22.6%、50.0%和15.0%）。总之，摩根菌血症最常与胆道感染相关，而变形杆菌菌血症最常与尿路感染相关。普罗威登斯菌血症相对少见，可与尿路感染以外的感染相关。
