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睡眠呼吸暂停:2002 - 2012年芬兰国家预防与治疗指南

Sleep apnoea: Finnish National guidelines for prevention and treatment 2002-2012.

作者信息

Laitinen L A, Anttalainen U, Pietinalho A, Hämäläinen P, Koskela K

机构信息

Hospital District of Helsinki and Uusimaa, Finland.

出版信息

Respir Med. 2003 Apr;97(4):337-65. doi: 10.1053/rmed.2002.1449.

Abstract

(1) After negotiations with the Finnish Ministry of Social Affairs and Health, a national programme to promote prevention, treatment and rehabilitation of sleep apnoea for the years 2002-2012 has been prepared by the Finnish Lung Health Association on the basis of extensive collaboration. The programme needs to be revised as necessary, because of the rapid development in medical knowledge, and in appliance therapy in particular. (2) Sleep apnoea deteriorates slowly. Its typical features are snoring, interruptions of breathing during sleep and daytime tiredness. Sleep apnoea affects roughly 3% of middle-aged men and 2% of women. In Finland, there are approx. 150,000 sleep apnea patients, of which 15,000 patients have a severe disease, 50,000 patients are moderate and 85,000 have a mild form of the disease. Children are also affected by sleep apnea. A typical sleep apnea patient is a middle-aged man or a postmenopausal woman. (3) The obstruction of upper airways is essential in the occurrence of sleep apnoea. The obstruction can be caused by structural and/or functional factors. As for structural factors, there are various methods of intervention, such as to secure children's nasal respiration, to remove redundant soft tissue, as well as to correct malocclusions. It is possible to have an effect on the functional factors by treating well diseases predisposing to sleep apnoea, by reducing smoking, the consumption of alcohol and the use of medicines impairing the central nervous system. The most important single risk factor for sleep apnoea is obesity. (4) Untreated sleep apnoea leads to an increase morbidity and mortality through heart circulatory diseases and through accidents by tiredness. Untreated or undertreated sleep apnoea deteriorates a person's quality of life and working capacity. (5) The goals of the Programme for the prevention and treatment of sleep apnoea are as follows: (1) to decrease the incidence of sleep apnoea, (2) to ensure that as many patients as possible with sleep apnoea recover, (3) to maintain capacity for work and functional capacity of patients with sleep apnoea, (4) to reduce the percentage of patients with severe sleep apnoea, (5) to decrease the number of sleep apnoea patients requiring hospitalisation and (6) to improve cost effectiveness of prevention and treatment of sleep apnoea. (6) The following means are suggested for achieving the goals: (1) to promote prevention of obesity, weight loss and weight control; (2) to promote securing of nasal respiration in child patients and removal of obstructing redundant soft tissues; (3) to promote the correction of children's malocclusions, (4) to enhance knowledge about risk factors and treatment of sleep apnoea in key groups, (5) to promote early diagnosis and active treatment, (6) to commence rehabilitation early and individually as a part of treatment and (7) to encourage scientific research. (7) On the national level, the occurrence of sleep apnoea can be prevented, for example, by encouraging weight control. The programme gives examples of such measures and appeals to various authorities and voluntary organisations to reinforce their collaboration. Preventive measures should be individualised, and based on due consideration. (8) The efficacy of diagnosing sleep apnoea should be increased. Attention should be paid to the symptoms of risk group patients at different units of the primary and occupational health care. Even mild forms of the disease should be treated appropriately. Diagnosis and treatment of the disease involve cooperation between the primary and specialised health-care sectors. Methods of treatment are (1) treatment of obesity, (2) positional therapy, (3) reduction of the use of medicines impairing the central nervous system, (4) reduction of smoking and the consumption of alcohol, (5) devices affecting the position of the tongue and lower jaw, (6) treatment with Continuous Positive Airway Pressure (CPAP-treatment), (7) surgical methods of treatment and (8) rehabilitation. (9) The hierarchy of referrals in the prevention and treatment of sleep apnoea should be revised to accord a greater role to the primary health-care sector. Good exchanges of information and cooperation between the primary health care and specialised medical-care sectors should be developed. Hospitals districts in cooperation with provincial governments and municipalities should ensure that different levels of the health-care system are capable of fulfilling the tasks assigned to them appropriately. (10) Rehabilitation of sleep apnoea should be goal-orientated and cover all forms of rehabilitation: medical, occupational and social. Rehabilitation should prevent the effects caused by the disease. Thus, it is possible to support self-care, increase the patient's resources and improve quality of life. (11) Information and training should be directed primarily towards health-care personnel, patients and their families. Organisations should produce materials for health and patient education as well as organising training events. To support the activities. financing will be needed from organisations such as Finland's Slot Machine Association. The Social Insurance Institution should disseminate information about questions of social security. Regional direction and training will mainly be the responsibilities of hospital districts, provincial governments and local health centres. The media will play an important role in the dissemination in-depth information about prevention and treatment of sleep apnoea.

摘要

(1) 经与芬兰社会事务与卫生部协商,芬兰肺部健康协会在广泛合作的基础上制定了2002 - 2012年全国性促进睡眠呼吸暂停预防、治疗及康复的计划。鉴于医学知识,尤其是器械治疗的快速发展,该计划需视情况进行修订。(2) 睡眠呼吸暂停发展缓慢。其典型特征为打鼾、睡眠中呼吸中断及日间疲劳。睡眠呼吸暂停约影响3%的中年男性和2%的女性。在芬兰,约有15万睡眠呼吸暂停患者,其中1.5万患者病情严重,5万患者为中度,8.5万患者病情较轻。儿童也会受睡眠呼吸暂停影响。典型的睡眠呼吸暂停患者为中年男性或绝经后女性。(3) 上气道阻塞在睡眠呼吸暂停的发生中至关重要。阻塞可由结构和/或功能因素引起。至于结构因素,有多种干预方法,如确保儿童鼻腔呼吸、去除多余软组织以及矫正错颌畸形。通过治疗易引发睡眠呼吸暂停的疾病、减少吸烟、饮酒及使用损害中枢神经系统的药物,可对功能因素产生影响。睡眠呼吸暂停最重要的单一风险因素是肥胖。(4) 未经治疗的睡眠呼吸暂停会通过心脏循环疾病和因疲劳导致的事故增加发病率和死亡率。未经治疗或治疗不足的睡眠呼吸暂停会降低人的生活质量和工作能力。(5) 睡眠呼吸暂停防治计划的目标如下:(1) 降低睡眠呼吸暂停的发病率;(2) 确保尽可能多的睡眠呼吸暂停患者康复;(3) 维持睡眠呼吸暂停患者的工作能力和功能能力;(4) 降低重度睡眠呼吸暂停患者的比例;(5) 减少需要住院治疗的睡眠呼吸暂停患者数量;(6) 提高睡眠呼吸暂停防治的成本效益。(6) 为实现这些目标建议采取以下措施:(1) 促进肥胖预防、体重减轻及体重控制;(2) 促进确保儿童患者的鼻腔呼吸及去除阻塞性多余软组织;(3) 促进矫正儿童错颌畸形;(4) 增强关键人群对睡眠呼吸暂停风险因素及治疗的认识;(5) 促进早期诊断和积极治疗;(6) 作为治疗的一部分尽早并个性化地开展康复;(7) 鼓励科学研究。(7) 在国家层面,例如通过鼓励体重控制可预防睡眠呼吸暂停的发生。该计划列举了此类措施的示例,并呼吁各相关当局和志愿组织加强合作。预防措施应个性化且基于适当考虑。(8) 应提高睡眠呼吸暂停的诊断效率。在初级和职业卫生保健的不同单位,应关注风险群体患者的症状。即使是疾病的轻度形式也应得到适当治疗。该疾病的诊断和治疗涉及初级和专科卫生保健部门之间的合作。治疗方法包括:(1) 肥胖治疗;(2) 体位疗法;(3) 减少使用损害中枢神经系统的药物;(4) 减少吸烟和饮酒;(5) 影响舌和下颌位置的器械;(6) 持续气道正压通气治疗(CPAP治疗);(7) 手术治疗方法;(8) 康复。(9) 应修订睡眠呼吸暂停防治中的转诊层级,赋予初级卫生保健部门更大作用。应发展初级卫生保健与专科医疗保健部门之间良好的信息交流与合作。医院区与省政府及市政府合作,应确保卫生保健系统的不同层级能够适当履行分配给它们的任务。(10) 睡眠呼吸暂停的康复应以目标为导向,涵盖所有形式的康复:医疗、职业和社会康复。康复应预防疾病造成的影响。因此,可支持自我护理、增加患者资源并改善生活质量。(11) 信息和培训应主要针对卫生保健人员、患者及其家属。各组织应制作卫生和患者教育材料,并组织培训活动。为支持这些活动,需要芬兰老虎机协会等组织提供资金。社会保险机构应传播有关社会保障问题的信息。区域指导和培训主要由医院区、省政府和地方卫生中心负责。媒体在深入传播睡眠呼吸暂停预防和治疗信息方面将发挥重要作用。

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