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细胞黏附分子在肝脏和肠道白细胞募集中的作用。

Role of cell adhesion molecules in leukocyte recruitment in the liver and gut.

作者信息

Ala A, Dhillon A P, Hodgson H J

机构信息

Centre for Hepatology, Department of Medicine, Royal Free & University College School of Medicine, Royal Free Campus, Rowland Hill Street, London NW3 2PF, UK.

出版信息

Int J Exp Pathol. 2003 Feb;84(1):1-16. doi: 10.1046/j.1365-2613.2003.00235.x.

DOI:10.1046/j.1365-2613.2003.00235.x
PMID:12694483
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2517541/
Abstract

This article reviews the evidence that adhesion molecules are critical in leukocyte recirculation and pathogenesis of diseases affecting the closely related tissues of the liver and gut, which offer novel opportunities for treatment.

摘要

本文综述了粘附分子在白细胞再循环以及影响肝脏和肠道密切相关组织的疾病发病机制中起关键作用的证据,这些证据为治疗提供了新的机会。

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A pilot study of treatment of active ulcerative colitis with natalizumab, a humanized monoclonal antibody to alpha-4 integrin.一项使用那他珠单抗(一种抗α-4整合素的人源化单克隆抗体)治疗活动性溃疡性结肠炎的试点研究。
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Homing of mucosal lymphocytes to the liver in the pathogenesis of hepatic complications of inflammatory bowel disease.黏膜淋巴细胞归巢至肝脏在炎症性肠病肝脏并发症发病机制中的作用
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Immune cell trafficking in uterus and early life is dominated by the mucosal addressin MAdCAM-1 in humans.在人类中,子宫和早期生命中的免疫细胞运输主要由黏膜地址素MAdCAM-1主导。
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Regulation and distribution of MAdCAM-1 in endothelial cells in vitro.体外内皮细胞中黏膜地址素细胞黏附分子-1(MAdCAM-1)的调控与分布
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Different patterns of beta-catenin expression in gastric carcinomas: relationship with clinicopathological parameters and prognostic outcome.胃癌中β-连环蛋白的不同表达模式:与临床病理参数及预后结果的关系
Histopathology. 2001 Aug;39(2):141-9. doi: 10.1046/j.1365-2559.2001.01177.x.
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Soluble adhesion molecules in inflammatory bowel disease.炎症性肠病中的可溶性黏附分子
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J Cell Biol. 2001 Jul 23;154(2):369-87. doi: 10.1083/jcb.200102028.
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Hepatology. 2001 May;33(5):1065-72. doi: 10.1053/jhep.2001.24231.
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Cutting edge: evidence for a signaling partnership between urokinase receptors (CD87) and L-selectin (CD62L) in human polymorphonuclear neutrophils.前沿:人多形核中性粒细胞中尿激酶受体(CD87)与L-选择素(CD62L)之间信号传导伙伴关系的证据
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