[胸腺切除8个月后诱导的过敏性休克成年豚鼠淋巴及内脏器官的组织形态学变化]

[Histomorphological changes in the lymphoid and internal organs of adult guinea pigs in anaphylactic shock, induced 8 months after thymectomy].

作者信息

Markov D, Kozarov I

出版信息

Eksp Med Morfol. 1976;15(1):18-23.

Abstract

Anaphylactic shock was induced in adult guinea pigs eight months after operative thymectomy. It was established that thymectomy caused depletion of lymphoid tissue with atrophy of lymphyc follicles and disappearence of germinative centers in the spleen, mesenterial lymph gland and intestinal lymph tissue. There was no anaphyactic shock in 81.2% of the thymectomized animals as a result of the inhibited immunoallergic reactivity, but dystrophic and inflammatory changes in their parenchymatous organs were more frequent and graver in comparison with the nonthymectomized animals.

摘要

成年豚鼠在胸腺切除术后八个月诱发过敏性休克。结果表明，胸腺切除导致淋巴组织耗竭，伴有脾、肠系膜淋巴结和肠淋巴组织中淋巴滤泡萎缩及生发中心消失。由于免疫过敏反应受到抑制，81.2%的胸腺切除动物未发生过敏性休克，但与未切除胸腺的动物相比，其实质器官中的营养不良和炎症变化更为频繁且严重。