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剖宫产术中不缝合腹膜:一项随机对照试验的长期随访

Nonclosure of the peritoneum during caesarean section: long-term follow-up of a randomised controlled trial.

作者信息

Roset Edith, Boulvain Michel, Irion Olivier

机构信息

Unité de Développement en Obstétrique, Departement of Obstetrics and Gynecology, Hopitaux Universitaires de Genève, University of Geneva, CH-1211 Geneva 14, Switzerland.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2003 May 1;108(1):40-4. doi: 10.1016/s0301-2115(02)00366-4.

Abstract

OBJECTIVE

To compare long-term morbidity of nonclosure and closure of the peritoneum at caesarean section.

STUDY DESIGN

Participants to a randomised controlled trial were contacted 7 years later. Outcome measures were assessed by a postal questionnaire and reports of subsequent operations.

RESULTS

We were able to contact 226 of the 280 women recruited initially, and 144 responded to the questionnaire. Sixty-nine had been allocated to nonclosure of the peritoneum and 75 to closure. Baseline characteristics at randomisation were comparable both between the respondents and the non-respondents, and between originally allocated groups. No statistically significant difference was found between the two groups regarding fertility, abdominal pain, and urinary symptoms. Among 29 reports of subsequent abdominal surgery, 14 mentioned the presence of adhesions (8 in the nonclosure and 6 in the closure group; P=0.47). The number of women reporting at least one significant morbidity was similar between groups (24 in the nonclosure and 19 in the closure group; P=0.72).

CONCLUSION

Nonclosure and closure of the peritoneum at caesarean section result in similar long-term morbidity.

摘要

目的

比较剖宫产术中不缝合与缝合腹膜的远期发病率。

研究设计

对一项随机对照试验的参与者在7年后进行随访。通过邮寄问卷调查和后续手术报告评估结局指标。

结果

我们成功联系到了最初招募的280名女性中的226名,其中144名回复了问卷。69名被分配至不缝合腹膜组,75名被分配至缝合腹膜组。随机分组时的基线特征在回复者与未回复者之间以及最初分配的组间具有可比性。两组在生育能力、腹痛和泌尿系统症状方面未发现统计学显著差异。在29份后续腹部手术报告中,14份提及存在粘连(不缝合腹膜组8例,缝合腹膜组6例;P = 0.47)。报告至少一种严重发病情况的女性数量在两组间相似(不缝合腹膜组24例,缝合腹膜组19例;P = 0.72)。

结论

剖宫产术中不缝合与缝合腹膜导致的远期发病率相似。

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