预测作为有机化合物化学结构以及主要物理和化学性质函数的生物效应。
Predicting biological effect as a function of the chemical structure and the primary physical and chemical properties of organic compounds.
作者信息
Andreyeshcheva N G
出版信息
Environ Health Perspect. 1976 Feb;13:27-30. doi: 10.1289/ehp.761327.
Abstract
The dependence of biological parameters on chemical structure was studied for a series of compounds with similar chemical structures. Computational formulas were developed on the basis of correlation and regression analysis. These formulas make it possible to predict the biological effect thresholds for a great number of organic compounds on the basis of their primary physical and chemical properties.
摘要
研究了一系列化学结构相似的化合物的生物学参数对化学结构的依赖性。基于相关性和回归分析得出了计算公式。这些公式使得基于大量有机化合物的基本物理和化学性质来预测其生物学效应阈值成为可能。
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