• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Differential effects of lipids on the osmotic fragility of lysosomes.

作者信息

Raz A, Goldman R

出版信息

Experientia. 1976 Apr 15;32(4):447-9. doi: 10.1007/BF01920787.

DOI:10.1007/BF01920787
PMID:1269643
Abstract

The effect of a wide range of concentrations of oleic acid, oleyl alcohol and oleic acid methyl ester on lysosomal stability has been studied under both hypotonic and isoosmotic medium conditions. Both oleic acid and oleyl alcohol exhibited a biphasic interaction pattern with lysosomes; stabilizing at low concentrations and labilizing at high concentrations. Lysosome labilization by the ester required an initial lag period.

摘要

相似文献

1
Differential effects of lipids on the osmotic fragility of lysosomes.
Experientia. 1976 Apr 15;32(4):447-9. doi: 10.1007/BF01920787.
2
Toxicity of free fatty acids for cultured rat heart muscle and endothelioid cells. II. Unsaturated long-chain fatty acids.游离脂肪酸对培养的大鼠心肌和内皮样细胞的毒性。II. 不饱和长链脂肪酸。
Toxicology. 1978 Oct;11(2):119-25. doi: 10.1016/s0300-483x(78)90839-9.
3
[Effect of various unsaturated fatty acids on the stability of the erythrocyte membrane in the rat].[不同不饱和脂肪酸对大鼠红细胞膜稳定性的影响]
Ann Nutr Metab. 1992;36(2):113-20. doi: 10.1159/000177705.
4
Osmotic stabilization of unsaturated fatty acid auxotrophs of Escherichia coli.大肠杆菌不饱和脂肪酸营养缺陷型的渗透稳定作用
J Biochem. 1974 Sep;76(3):553-61. doi: 10.1093/oxfordjournals.jbchem.a130599.
5
3'-5'-cAMP and lysosome membrane labilization.3'-5'-环磷酸腺苷与溶酶体膜不稳定化
Experientia. 1972 May 15;28(5):513-4. doi: 10.1007/BF01931849.
6
Structure- and configuration-dependent effects of C18 unsaturated fatty acids on the chicken and sheep erythrocyte membrane.
Biochim Biophys Acta. 1984 Feb 15;769(3):571-7. doi: 10.1016/0005-2736(84)90055-5.
7
Mechanisms of loss of latency of lysosomal enzymes. Effects of incubation on the properties of lysosomal membranes.溶酶体酶潜伏时间丧失的机制。孵育对溶酶体膜性质的影响。
Biochem J. 1980 Jan 15;186(1):243-56. doi: 10.1042/bj1860243.
8
Mechanism of action of miconazole: labilization of rat liver lysosomes in vitro by miconazole.咪康唑的作用机制:咪康唑在体外使大鼠肝脏溶酶体不稳定。
Antimicrob Agents Chemother. 1976 Jun;9(6):903-7. doi: 10.1128/AAC.9.6.903.
9
Acid phosphatase residual latent activity versus lysosome osmotic fragility in rat liver autophagy.大鼠肝脏自噬中酸性磷酸酶残余潜伏活性与溶酶体渗透脆性的关系
Exp Mol Pathol. 1982 Aug;37(1):133-9. doi: 10.1016/0014-4800(82)90029-6.
10
Studies on gentamicin-induced labilization of rat kidney lysosomes in vitro. Possible protection by selenium.庆大霉素体外诱导大鼠肾溶酶体不稳定的研究。硒的可能保护作用。
Biochem Pharmacol. 1983 Sep 15;32(18):2659-64. doi: 10.1016/0006-2952(83)90072-2.

本文引用的文献

1
Effects of fat-soluble compounds on lysosomes in vitro.脂溶性化合物在体外对溶酶体的影响。
Biochem Pharmacol. 1962 Aug;9:97-116. doi: 10.1016/0006-2952(62)90015-1.
2
Interaction of lysosomes and anti-infalmmatory drugs.溶酶体与抗炎药物的相互作用。
Proc Soc Exp Biol Med. 1969 Jun;131(2):614-20. doi: 10.3181/00379727-131-33938.
3
Suppression of enzyme release from isolated rat liver lysosomes by non-steroidal anti-inflammatory drugs.非甾体抗炎药对离体大鼠肝溶酶体酶释放的抑制作用。
Biochem Pharmacol. 1968 Oct;17(10):2023-32. doi: 10.1016/0006-2952(68)90175-5.
4
Studies in vitro and in vivo of the effects of chlorpromazine on rat liver lysosomes.氯丙嗪对大鼠肝脏溶酶体影响的体内外研究。
Biochem Pharmacol. 1965 May;14(5):769-75. doi: 10.1016/0006-2952(65)90095-x.
5
Effects of anti-inflammatory drugs on the stability of rat liver lysosomes in vitro.抗炎药物对大鼠肝溶酶体体外稳定性的影响。
Biochem Pharmacol. 1971 Oct;20(10):2847-60. doi: 10.1016/0006-2952(71)90196-1.
6
Effect of hashish compounds on rat liver lysosomes in vitro.大麻化合物对大鼠肝脏溶酶体的体外作用。
Biochem Pharmacol. 1973 Dec 1;22(23):3129-31. doi: 10.1016/0006-2952(73)90204-9.
7
Differential effects of lipids on the osmotic fragility of erythrocytes.
Biochim Biophys Acta. 1973 Jun 22;311(2):222-9. doi: 10.1016/0005-2736(73)90269-1.
8
The membrane actions of anesthetics and tranquilizers.麻醉剂和镇静剂的膜作用。
Pharmacol Rev. 1972 Dec;24(4):583-655.
9
Progesterone-induced permeability changes in rat liver lysosomes.孕酮诱导大鼠肝脏溶酶体的通透性变化。
Nat New Biol. 1973 Mar 28;242(117):123-4. doi: 10.1038/newbio242123a0.
10
Osmotic fragility of liposomes as affected by antihelmolytic compounds.抗溶血化合物对脂质体渗透脆性的影响
Biochim Biophys Acta. 1974 Feb 26;339(1):146-55. doi: 10.1016/0005-2736(74)90340-x.