Dolev Eran
Harefuah. 2003 Mar;142(3):186-7, 239, 238.
Thalidomide, a medication the use of which was banned about forty years ago due to its teratogenic effect, has returned into use due to its anti-angiogenic and immunomodulatory virtues. It is used now as a novel treatment in several malignant diseases as well as in the treatment of various inflammatory conditions. Recently it has been found that thalidomide may antagonize corneal blood vessels growth which is a late results of exposure to mustard gas. The story of thalidomide, which is very unusual, may serve as the snake symbol in medicine, to remind us about the possible double face of every medication, of which every physician should be aware.
沙利度胺是一种约四十年前因其致畸作用而被禁用的药物，如今因其抗血管生成和免疫调节特性又重新投入使用。它目前被用作多种恶性疾病的新型治疗药物以及用于治疗各种炎症性疾病。最近发现沙利度胺可能拮抗角膜血管生长，角膜血管生长是接触芥子气的晚期后果。沙利度胺的故事非常特别，它可作为医学领域的蛇的象征，提醒我们每种药物都可能有两面性，每位医生都应有所认识。
