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[首份SIVR参考值列表:定义、方法学标准及分析策略]

[First SIVR list of reference values: definitions, methodologic criteria and analytical strategies].

作者信息

Minoia C, Apostoli P

机构信息

Laboratorio di Igiene Ambientale e Tossicologia Industriale, Fondazione S. Maugeri, Clinica del Lavoro e della Riabilitazione, IRCCS, Istituto Scientifico di Pavia.

出版信息

G Ital Med Lav Ergon. 2003 Jan-Mar;25(1):15-21.

PMID:12696482
Abstract

In this paper, a list of reference values for trace elements and some of the main organic xenobiotics and/or their metabolites in biological matrices (urine, serum or blood) is presented. This list has been made out taking into account several variables, such as sex, diet, alcohol and drugs consumption, smoking habits, living area, etc. and it is referred to as the 1st SIVR list 2001. In addition, the SIVR research activity is reassessed on the basis of the availability of multielement techniques and new analytical approaches. In particular, to define the reference values for PCB, selection criteria and analytical methodologies are discussed with a view to choosing the more significant congeners and the most suitable technique. In the end, the results from two SIVR projects concerning the determination of haematic Pb and urinary Hg are synthesized.

摘要

本文列出了生物基质(尿液、血清或血液)中微量元素以及一些主要有机外来化合物和/或其代谢物的参考值列表。该列表的制定考虑了多个变量,如性别、饮食、酒精和药物消费、吸烟习惯、居住地区等,被称为2001年第一份SIVR列表。此外,根据多元素技术和新分析方法的可用性对SIVR研究活动进行了重新评估。特别是,为了确定多氯联苯的参考值,讨论了选择标准和分析方法,以便选择更具代表性的同系物和最合适的技术。最后,综合了两个关于测定血液中铅和尿液中汞的SIVR项目的结果。

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