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粗针活检在软组织肿瘤诊断中的价值。

Value of core needle biopsy in the diagnosis of soft tissue tumours.

作者信息

Madhavan V P, Smile S Robinson, Chandra S Sarath, Ratnakar C

机构信息

Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry.

出版信息

Indian J Pathol Microbiol. 2002 Apr;45(2):165-8.

Abstract

We performed a prospective study to determine the accuracy of core needle biopsy in the diagnosis and grading of soft tissue tumours and to study the morbidity of core needle biopsy. Forty one cases of soft tissue tumours, 24 of them malignant and 17 benign, were biopsied with an 18G core needle. Core needle biopsy reports were compared with the final histopathological report after definitive procedure or incisional biopsy. 85.3% of core biopsies yielded adequate sample. Core needle biopsy had a sensitivity of 90%, specificity of 100%, positive predictive value of 100% and a negative predictive value of 88.23%. Overall accuracy for diagnosis of malignancy was 94.28%, 77.7% of tumours were correctly subtyped and none of them were histologically graded. There was no immediate complication of haemorrhage in any of the cases. Thus, we conclude that core needle biopsy is equivalent to incisional biopsy in diagnostic accuracy and being simple, less expensive and unlikely to compromise further management, can be used in place of open biopsy of soft tissue tumours.

摘要

我们进行了一项前瞻性研究,以确定粗针活检在软组织肿瘤诊断和分级中的准确性,并研究粗针活检的发病率。41例软组织肿瘤患者接受了18G粗针活检,其中24例为恶性,17例为良性。将粗针活检报告与最终手术或切开活检后的组织病理学报告进行比较。85.3%的粗针活检获得了足够的样本。粗针活检的敏感性为90%,特异性为100%,阳性预测值为100%,阴性预测值为88.23%。恶性肿瘤诊断的总体准确率为94.28%,77.7%的肿瘤被正确分型,且均未进行组织学分级。所有病例均无立即出血并发症。因此,我们得出结论,粗针活检在诊断准确性方面与切开活检相当,且操作简单、成本较低,不太可能影响进一步治疗,可用于替代软组织肿瘤的开放活检。

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