Pramesh C S, Deshpande M S, Pardiwala D N, Agarwal M G, Puri A
Department of Surgical Oncology, Bone and Soft Tissue Services, Tata Memorial Hospital, Mumbai 400 012, India.
Eur J Surg Oncol. 2001 Nov;27(7):668-71. doi: 10.1053/ejso.2001.1198.
Percutaneous core biopsy of bone lesions provides early and definitive diagnosis and guides decisions on management. It is an inexpensive examination technique and has negligible complication rates.
We performed a prospective study of 136 patients who underwent core biopsies for bone lesions over an 18-month period. A Jamshidi (J) needle was used to obtain a core of tissue and specimens were sent for histopathological examination. Biopsy results were analysed for adequacy, ability to yield diagnostic information and for accuracy of diagnosis.
The mean age of patients was 27.5 years with a range of 3-72 years. There were 84 males and 52 females in the study. Histopathological diagnosis was obtained in 121 (89%) patients. The specimen was non-diagnostic in 15 patients. Fourteen patients required two attempts and two patients required three attempts at biopsy. Sixty-two of 64 patients (96.9%) who had a confirmed final diagnosis had an accurate J-needle histopathological diagnosis. None of the patients had any major complications.
Core needle biopsy is an important tool in the evaluation of bone lesions. It is a safe, reliable and accurate procedure and yields diagnostic information in a high proportion of patients. It has several advantages over an open bone biopsy.
骨病变的经皮芯针活检可提供早期明确诊断，并指导治疗决策。它是一种廉价的检查技术，并发症发生率可忽略不计。
我们对136例在18个月期间接受骨病变芯针活检的患者进行了一项前瞻性研究。使用Jamshidi（J）针获取组织芯，并将标本送去进行组织病理学检查。分析活检结果的充分性、产生诊断信息的能力以及诊断的准确性。
患者的平均年龄为27.5岁，范围为3至72岁。研究中有84名男性和52名女性。121例（89%）患者获得了组织病理学诊断。15例患者的标本未得出诊断结果。14例患者需要进行两次活检尝试，2例患者需要进行三次活检尝试。在64例最终确诊的患者中，62例（96.9%）通过J针组织病理学诊断准确。所有患者均未出现任何严重并发症。
芯针活检是评估骨病变的重要工具。它是一种安全、可靠且准确的方法，在很大比例的患者中能产生诊断信息。与开放性骨活检相比有多个优点。
