Hayashida M, Chinzei M, Komatsu K, Yamamoto H, Tamai H, Orii R, Hanaoka K, Murakami A
Department of Anaesthesiology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Japan.
Br J Anaesth. 2003 May;90(5):694-8. doi: 10.1093/bja/aeg107.
The bispectral index (BIS) may indicate changes in cerebral activity when the cerebral circulation is affected by acute hypotension.
We measured BIS and cerebral haemoglobin saturation (Sr(O(2))) by near-infrared spectroscopy in 10 children undergoing cardiac surgery.
We noted 14 episodes of simultaneous decreases in Sr(O(2)) and BIS during acute hypotension in five children. An acute decrease in BIS, which coincided with a decrease in Sr(O(2)) suggesting a reduction in cerebral blood flow, was associated with acute slowing of the raw EEG waveforms.
Our findings suggest that an acute decrease in BIS during acute hypotension indicates cerebral hypoperfusion, and that cerebral hypoperfusion caused by hypotension may occur frequently during paediatric cardiac surgery.
当脑循环受到急性低血压影响时,脑电双频指数(BIS)可能表明脑活动的变化。
我们对10名接受心脏手术的儿童,通过近红外光谱法测量了BIS和脑血红蛋白饱和度(Sr(O₂))。
我们注意到5名儿童在急性低血压期间,有14次Sr(O₂)和BIS同时下降的情况。BIS的急性下降与Sr(O₂)的下降同时出现,提示脑血流量减少,这与原始脑电图波形的急性减慢有关。
我们的研究结果表明,急性低血压期间BIS的急性下降表明脑灌注不足,并且在小儿心脏手术期间,由低血压引起的脑灌注不足可能经常发生。