Lee Brian L, Wilson M Roy
Creighton University School of Medicine, Omaha, Nebraska 68178, USA.
Curr Opin Ophthalmol. 2003 Apr;14(2):74-7. doi: 10.1097/00055735-200304000-00003.
To summarize the major findings of the Ocular Hypertension Treatment Study (OHTS).
Ocular hypertensive subjects who received topical glaucoma medication experienced conversion to glaucoma at less than half the rate of subjects who were monitored without treatment. Risk factors for converting to glaucoma included older age, higher intraocular pressure, larger cup-disc ratio, higher pattern SD, and thinner central corneal thickness.
The OHTS clearly established that medically treating ocular hypertension is efficacious in delaying or preventing the onset of glaucoma. Further, the results may assist in providing useful guidelines for determining who with ocular hypertension should be offered medical treatment.
总结眼压升高治疗研究(OHTS)的主要发现。
接受局部青光眼药物治疗的眼压升高患者发生青光眼的转化率不到未接受治疗而仅接受监测患者的一半。转化为青光眼的危险因素包括年龄较大、眼压较高、杯盘比更大、图形标准差较高以及中央角膜厚度较薄。
OHTS明确证实,药物治疗眼压升高在延缓或预防青光眼发作方面是有效的。此外,这些结果可能有助于为确定哪些眼压升高患者应接受药物治疗提供有用的指导方针。