阿司匹林对正常受试者胃前列腺素E（PGE）及胃酸分泌的影响。
Effects of aspirin on gastric prostaglandin E (PGE) and acid output in normal subjects.
作者信息
Child C, Jubiz W, Moore J G
出版信息
Gut. 1976 Jan;17(1):54-7. doi: 10.1136/gut.17.1.54.
Abstract
Aspirin administration to normal subjects resulted in a reduction in gastric prostaglandin E (PGE) output. Both PGE concentration and gastric juice volume were decreased. Gastric acid output also decreased, although the difference was not statistically significant. An increased sensitivity of the PGE system to inhibition by aspirin at 11 p.m., midnight, and 1am was observed.
摘要
对正常受试者服用阿司匹林会导致胃前列腺素E（PGE）分泌减少。PGE浓度和胃液量均降低。胃酸分泌也减少，尽管差异无统计学意义。观察到PGE系统在晚上11点、午夜和凌晨1点时对阿司匹林抑制作用的敏感性增加。
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