G蛋白β3亚基基因C825T多态性的影响：关于增强G蛋白激活潜在分子机制的假说是否应修订？聚焦于“与疾病状态相关的G蛋白β3亚基剪接变体不调节离子通道” - Suppr | 超能文献

Effects of the G protein beta 3-subunit gene C825T polymorphism: should hypotheses regarding the molecular mechanisms underlying enhanced G protein activation be revised? Focus on "A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels".

作者信息

Siffert Winfried

出版信息

Physiol Genomics. 2003 Apr 16;13(2):81-4. doi: 10.1152/physiolgenomics.00031.2003.

DOI:10.1152/physiolgenomics.00031.2003

Abstract

摘要

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1

Effects of the G protein beta 3-subunit gene C825T polymorphism: should hypotheses regarding the molecular mechanisms underlying enhanced G protein activation be revised? Focus on "A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels".G蛋白β3亚基基因C825T多态性的影响：关于增强G蛋白激活潜在分子机制的假说是否应修订？聚焦于“与疾病状态相关的G蛋白β3亚基剪接变体不调节离子通道”

Physiol Genomics. 2003 Apr 16;13(2):81-4. doi: 10.1152/physiolgenomics.00031.2003.

2

A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels.一种与疾病状态相关的G蛋白β3亚基剪接变体不调节离子通道。

Physiol Genomics. 2003 Apr 16;13(2):85-95. doi: 10.1152/physiolgenomics.00057.2002.

3

Identification and characterization of G beta 3s2, a novel splice variant of the G-protein beta 3 subunit.G蛋白β3亚基的一种新型剪接变体G beta 3s2的鉴定与特征分析。

Biochem J. 2003 Apr 1;371(Pt 1):223-32. doi: 10.1042/BJ20021208.

4

Matrix analysis for the dissection of interactions of G-protein beta3 subunit C825T genotype, allograft function, and posttransplant hypertension in kidney transplantation.

Am J Kidney Dis. 2002 Dec;40(6):1319-24. doi: 10.1053/ajkd.2002.36913.

5

G protein beta 3 subunit gene variants and essential hypertension in the northern Chinese Han population.中国北方汉族人群中G蛋白β3亚基基因变异与原发性高血压的关系

Ann Hum Genet. 2005 Jul;69(Pt 4):468-73. doi: 10.1111/j.1529-8817.2005.00172.x.

6

Effect of the C825T polymorphism of the G protein beta 3 subunit on the systolic blood pressure-lowering effect of clonidine in young, healthy male subjects.G蛋白β3亚基C825T多态性对可乐定在年轻健康男性受试者中降低收缩压作用的影响。

Clin Pharmacol Ther. 2003 Jul;74(1):53-60. doi: 10.1016/S0009-9236(03)00087-0.

7

G protein beta3 subunit gene polymorphism in Turkish hypertensives.土耳其高血压患者中G蛋白β3亚基基因多态性

Anadolu Kardiyol Derg. 2008 Oct;8(5):331-5.

8

Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia.G蛋白β3亚基基因（GNB3）的C825T多态性与精神分裂症患者使用抗精神病药物后的临床改善之间存在提示性关联。

Eur Neuropsychopharmacol. 2005 Oct;15(5):525-31. doi: 10.1016/j.euroneuro.2005.02.001. Epub 2005 Apr 14.

9

Translating G protein subunit diversity into functional specificity.将G蛋白亚基多样性转化为功能特异性。

Curr Opin Cell Biol. 2004 Apr;16(2):206-9. doi: 10.1016/j.ceb.2004.02.007.

10

C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity.G蛋白β3亚基的C825T多态性与肥胖相关，但与胰岛素敏感性无关。

Obes Res. 2004 Apr;12(4):679-83. doi: 10.1038/oby.2004.78.

引用本文的文献

1

Analysis of HCRTR2, GNB3, and ADH4 Gene Polymorphisms in a Southeastern European Caucasian Cluster Headache Population.分析东南欧白种人丛集性头痛人群中 HCRTR2、GNB3 和 ADH4 基因的多态性。

J Mol Neurosci. 2020 Mar;70(3):467-474. doi: 10.1007/s12031-019-01439-0. Epub 2019 Nov 25.

2

Association of the GNB3 825T-allele with better survival in patients with glioblastoma multiforme.胶质母细胞瘤患者中GNB3 825T等位基因与更好的生存率之间的关联。

J Cancer Res Clin Oncol. 2010 Sep;136(9):1423-9. doi: 10.1007/s00432-010-0797-8. Epub 2010 Feb 10.

3

Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses.α2C肾上腺素能受体和G蛋白中的基因变异导致心血管应激反应存在种族差异。

Pharmacogenet Genomics. 2008 Sep;18(9):743-50. doi: 10.1097/FPC.0b013e3282fee5a1.