• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Dynamics of viral load rebound in plasma and semen after stopping effective antiretroviral therapy.

作者信息

Liuzzi Giuseppina, D'Offizi Gianpiero, Topino Simone, Zaccarelli Mauro, Amendola Alessandra, Capobianchi Maria Rosaria, Perno Carlo Federico, Narciso Pasquale, Antinori Andrea

机构信息

National Institute for Infectious Diseases L. Spallanzani, Rome, Italy.

出版信息

AIDS. 2003 May 2;17(7):1089-92. doi: 10.1097/00002030-200305020-00022.

DOI:10.1097/00002030-200305020-00022
PMID:12700463
Abstract

A rebound in the plasma and seminal viral load was detected in 12 patients after the interruption of effective highly active antiretroviral therapy. The viral rebound was generally higher in plasma, although the highest level observed during interruption was higher in semen in two patients. The reintroduction of therapy was followed by an overall decrease in HIV-RNA in plasma and semen. One to 2 months after restarting treatment, four out of seven patients showed undetectable HIV-RNA in semen.

摘要

相似文献

1
Dynamics of viral load rebound in plasma and semen after stopping effective antiretroviral therapy.
AIDS. 2003 May 2;17(7):1089-92. doi: 10.1097/00002030-200305020-00022.
2
Persistent HIV RNA shedding in semen despite effective antiretroviral therapy.尽管进行了有效的抗逆转录病毒治疗，但精液中仍持续存在 HIV RNA。
AIDS. 2009 Sep 24;23(15):2050-4. doi: 10.1097/QAD.0b013e3283303e04.
3
Discordance in HIV-1 viral loads and antiretroviral drug concentrations comparing semen and blood plasma.比较精液和血浆中 HIV-1 病毒载量和抗逆转录病毒药物浓度的不协调性。
HIV Med. 2009 Oct;10(9):548-54. doi: 10.1111/j.1468-1293.2009.00725.x. Epub 2009 Jun 8.
4
Seminal reservoirs during an HIV type 1 eradication trial.1型人类免疫缺陷病毒根除试验期间的精囊
AIDS Res Hum Retroviruses. 2005 Sep;21(9):768-75. doi: 10.1089/aid.2005.21.768.
5
HIV RNA Rebound in Seminal Plasma after Antiretroviral Treatment Interruption.抗逆转录病毒治疗中断后精液中 HIV RNA 的反弹。
J Virol. 2020 Jul 16;94(15). doi: 10.1128/JVI.00415-20.
6
Dynamics of viral load rebound and immunological changes after stopping effective antiretroviral therapy.停止有效抗逆转录病毒治疗后病毒载量反弹及免疫变化的动态情况
AIDS. 1999 Jul 30;13(11):F79-86. doi: 10.1097/00002030-199907300-00002.
7
Assisted reproduction in HIV-1-serodifferent couples: the need for viral validation of processed semen.HIV-1血清学不同夫妇的辅助生殖：对处理后精液进行病毒验证的必要性。
AIDS. 2002 Nov 22;16(17):2267-73. doi: 10.1097/00002030-200211220-00006.
8
Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma.在血浆中HIV-1 RNA检测不到的接受治疗患者的精液样本中检测HIV-1 RNA。
AIDS. 2008 Aug 20;22(13):1677-9. doi: 10.1097/QAD.0b013e32830abdc8.
9
Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma on a 2002-2011 survey.检测 2002-2011 年调查中血血浆 HIV-1 RNA 不可检测经治患者精浆样本中的 HIV-1 RNA。
AIDS. 2012 May 15;26(8):971-5. doi: 10.1097/QAD.0b013e328352ae09.
10
HIV-1 viral rebound dynamics after a single treatment interruption depends on time of initiation of highly active antiretroviral therapy.单次治疗中断后HIV-1病毒反弹动力学取决于高效抗逆转录病毒疗法开始的时间。
AIDS. 2008 Aug 20;22(13):1583-8. doi: 10.1097/QAD.0b013e328305bd77.

引用本文的文献

1
Genetic characterization of HIV-1 from semen and blood from clade C-infected subjects from India and effect of therapy in these body compartments.印度 C 型 HIV-1 感染者精液和血液中 HIV-1 的遗传特征及其在这些身体部位的治疗效果。
Virology. 2010 Jun 5;401(2):190-6. doi: 10.1016/j.virol.2010.01.033. Epub 2010 Mar 15.