Wijdicks Eelco F M, Manno Edward M, Fulgham Jimmy R, Giannini Caterina
Neurology Critical Care Service, Department of Neurology, Saint Marys Hospital, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
J Neurol. 2003 Apr;250(4):444-8. doi: 10.1007/s00415-003-1021-4.
Posterior leukoencephalopathy typically denotes neurotoxicity from immunosuppressive agents, malignant hypertension or eclampsia. It has not been documented in central nervous system angiitis. We present three cases associated with isolated cerebral angiitis after review of all cases of isolated CNS angiitis from 1998 to 2000. Additional lesions beyond the posterior occipital lesions became evident in two cases. A cerebral angiogram and possibly brain biopsy to detect isolated angiitis should be considered in patients with posterior leukoencephalopathy of unknown etiology.
后部白质脑病通常指免疫抑制剂、恶性高血压或子痫引起的神经毒性。中枢神经系统血管炎中尚未有相关记载。我们回顾了1998年至2000年所有孤立性中枢神经系统血管炎病例，现报告3例与孤立性脑血管炎相关的病例。2例患者除枕叶后部病变外，还出现了其他明显病变。对于病因不明的后部白质脑病患者，应考虑进行脑血管造影检查，可能还需进行脑活检以检测孤立性血管炎。
