Wehrmann T, Martchenko K, Menke D, Lange P, Stergiou N
Medizinische Klinik I, Klinikum Hannover-Siloah, Hannover.
Dtsch Med Wochenschr. 2003 Apr 17;128(16):863-9. doi: 10.1055/s-2003-38703.
This study assesses the value of intraductal ultrasound (IDUS) when the findings of endoscopic retrograde cholangio-pancreatography (ERCP) are unclear.
IDUS was performed over a two-year period in cases of bile duct or pancreatic duct stenosis of unknown origin found during ERCP or if cholelithiasis was suspected but ERC was seemingly normal. Duct stenoses were classified,before and after IDUS, as benign or malignant ductal or malignant extraductal, the findings then being checked by clinical follow-up,histology or, if bile duct stones had been suspected, by instrumental bile duct exploration.
Among 1303 ERCP investigations IDUS was attempted in 125 patients (9.6%; average age 60+/-14 years; 62 females). IDUS failed in seven patients for technical reasons (failure rate 6%). IDUS took an average time of 9+/-3 min. ERCP plus IDUS provided correct classification in 52 of 60 patients with bile duct stenosis (87%), and in 14 of 16 (88%) patients with pancreatic duct stenosis.ERCP alone correctly classified duct stenosis in 54 of 76 patients(87%), but in 66 of 76 (87%) with additional IDUS. The correct demonstration or exclusion of choledocholithiasis was obtained by IDUS in 40 of 42 patients (95%). Thus IDUS changed the diagnosis made by ERCP in 28 of 118 patients (24%).
With minor expenditure of time and an acceptable failure rate, additional IDUS after ERCP increases the diagnostic accuracy in cases where ductal stenosis or bile duct stones have not been clearly demonstrated.
本研究评估当内镜逆行胰胆管造影(ERCP)结果不明确时,胆管内超声(IDUS)的价值。
在两年时间内,对ERCP检查中发现的不明原因胆管或胰管狭窄病例,或怀疑有胆石症但ERCP看似正常的病例进行IDUS检查。在IDUS检查前后,将导管狭窄分为良性或恶性导管性或恶性导管外性,然后通过临床随访、组织学检查,或者如果怀疑有胆管结石,则通过器械胆管探查来检查结果。
在1303例ERCP检查中,对125例患者(9.6%;平均年龄60±14岁;62例女性)尝试进行IDUS检查。7例患者因技术原因IDUS检查失败(失败率6%)。IDUS平均耗时9±3分钟。ERCP联合IDUS在60例胆管狭窄患者中的52例(87%)以及16例胰管狭窄患者中的14例(88%)中提供了正确分类。单独ERCP在76例患者中的54例(87%)中正确分类了导管狭窄,但在76例中有66例(87%)联合IDUS检查。IDUS在42例患者中的40例(95%)中正确显示或排除了胆总管结石。因此,IDUS改变了118例患者中28例(24%)由ERCP做出的诊断。
ERCP后附加IDUS检查只需少量时间且失败率可接受,在导管狭窄或胆管结石未明确显示的病例中可提高诊断准确性。