人类神经肌肉疾病的肋间肌活检。组织化学和电子显微镜研究。
Intercostal muscle biopsy in human neuromuscular disease. Histochemical and electron microscopic studies.
作者信息
Stern L Z, Payne C M, Gruener R, Anderson R M, Hannapel L K
出版信息
J Neurol Neurosurg Psychiatry. 1975 Sep;38(9):900-10. doi: 10.1136/jnnp.38.9.900.
Abstract
External intercostal muscle biopsies were examined histochemically and by electron microscopy. The use of this muscle allowed correlation with physiological and pharmacological studies on the same specimens. Changes observed in musclar dystrophy and motor neurone disease resembled those previously described in biopsied limb muscle and underline the particular usefulness of this preparation in the study of human neuromuscular disease.
摘要
对肋间外肌活检标本进行了组织化学和电子显微镜检查。使用该肌肉可与对相同标本进行的生理学和药理学研究相关联。在肌肉萎缩症和运动神经元疾病中观察到的变化与先前在活检肢体肌肉中描述的变化相似，这突出了该标本制备方法在人类神经肌肉疾病研究中的特殊用途。
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