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子宫颈和阴道中肾病变的免疫病理学研究

Immunopathological study of mesonephric lesions of cervix uteri and vagina.

作者信息

Kondi-Pafitis A, Kairi E, Kontogianni K I, Dimopoulou C, Sikiotis K, Smyrniotis V

机构信息

Pathology Laboratory and 2nd Clinic of Obstetrics and Gynecology, Areteion University Hospital, Athens Medical School Athens, Greece.

出版信息

Eur J Gynaecol Oncol. 2003;24(2):154-6.

Abstract

Seventeen cases of mesonephric cervical remnants, four cases of mesonephric cervical carcinoma and nine vaginal Gardner cysts were studied by histochemical and immunohistochemical methods for the presence of mucin, proteoglucans, glucogen, CEA, cytokeratins, secretory component and vimentin. Mesonephric lesions in contrast to endocervical glandular lesions are negative for mucin, glucogen, CEA, and secretory component and positive for vimentin, and broad spectrum cytokeratins. Mesonephric carcinomas present certain immunopathological characteristics that permit their identification and proper treatment.

摘要

采用组织化学和免疫组织化学方法,对17例中肾管宫颈残余、4例中肾管宫颈癌和9例阴道加德纳囊肿进行了研究,以检测黏蛋白、蛋白聚糖、糖原、癌胚抗原(CEA)、细胞角蛋白、分泌成分和波形蛋白的存在情况。与宫颈腺性病变相比,中肾管病变的黏蛋白、糖原、CEA和分泌成分呈阴性,波形蛋白和广谱细胞角蛋白呈阳性。中肾管癌具有某些免疫病理特征,有助于其识别和恰当治疗。

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