与他莫昔芬使用相关的子宫肉瘤：病例报告。
Uterine sarcoma associated with tamoxifen use: case report.
作者信息
Martin-Loeches M, Rius J, Orti R M
机构信息
Department of Gynaecology, Marina Alta University Hospital, Alicante, Spain.
出版信息
Eur J Gynaecol Oncol. 2003;24(2):202-3.
A case of müllerian adenosarcoma with sarcomatous overgrowth in a postmenopausal 66-year-old female patient after adjuvant tamoxifen treatment for breast carcinoma is described. The patient was asymptomatic and the neoplasm was detected by pelvic sonography. The diagnosis was based on the histological findings after curettage and complementary total hysterectomy with bilateral salpingo-oophorectomy. The association of tamoxifen use and development of mesenchymal neoplasms is discussed.
本文描述了一例66岁绝经后女性患者，在接受乳腺癌辅助他莫昔芬治疗后发生的伴有肉瘤过度生长的苗勒管腺肉瘤。患者无症状，肿瘤通过盆腔超声检查发现。诊断基于刮宫及补充性全子宫切除术加双侧输卵管卵巢切除术后的组织学检查结果。文中讨论了他莫昔芬的使用与间叶性肿瘤发生之间的关联。
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