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[血液系统疾病脾切除术的预后因素]

[Prognostic factors for splenectomy for hematologic diseases].

作者信息

Hani Mohamed Aziz, Ben Achour Jamel, Zribi Riadh, Sghairoun Nada, Zoghlami Ayoub, Daghfous Mounir, Najah Nabil

机构信息

Service de Chirurgie Beau Séjour, Hôpital Charles Nicolle, Tunis.

出版信息

Tunis Med. 2002 Aug;80(8):485-8.

Abstract

The aim of this study was to identify the prognostic factors of intraoperative haemorrhage, perioperative blood transfusions and morbidity. We collected 120 splenectomies in Beau Séjour department of surgery, Charles' Nicolle Hospital, Tunis, Tunisia between 1979 and 1999. The descriptive analysis showed sex-ratio 0.82 with mean age (+/- standard deviation) 30.6 +/- 15 year. Idiopathic thrombopenic purpura was the principal disease indicating splenectomy. Morbidity was defined as occurrence of post operative peritoneal sepsis or bleeding. The mortality and morbidity rates were respectively 0.8% and 6.6%. The prognostic analysis didn't identify predictive factors of intraoperative haemorrhage, however it identified two independent predictive actors of specific morbidity: intraoperative haemorrhage (p = 0.03) and preoperative rate of haemoglobin (p = 0.0049).

摘要

本研究的目的是确定术中出血、围手术期输血和发病率的预后因素。我们收集了1979年至1999年间突尼斯突尼斯市查尔斯·尼科勒医院博·塞茹尔外科的120例脾切除术病例。描述性分析显示,性别比为0.82,平均年龄(±标准差)为30.6±15岁。特发性血小板减少性紫癜是脾切除术的主要指征。发病率定义为术后发生腹膜感染或出血。死亡率和发病率分别为0.8%和6.6%。预后分析未确定术中出血的预测因素,但确定了特定发病率的两个独立预测因素:术中出血(p = 0.03)和术前血红蛋白水平(p = 0.0049)。

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