Rakonczay Zoltán, Takács Tamás, Boros Imre, Lonovics János
First Department of Medicine, University of Szeged, Hungary.
J Cell Physiol. 2003 Jun;195(3):383-91. doi: 10.1002/jcp.10268.
Heat shock proteins (HSPs) are cytoprotective molecules that help to maintain the metabolic and structural integrity of cells. In this review, we briefly discuss the regulation and function of HSPs. The review focuses on the current knowledge of pancreatic HSP induction, the HSP level changes during acute pancreatitis, the potential effects of the pre- and co-induction of HSPs in experimental acute pancreatitis, and the mechanisms by which HSPs might mediate cellular protection.
热休克蛋白（HSPs）是一种细胞保护分子，有助于维持细胞的代谢和结构完整性。在本综述中，我们简要讨论热休克蛋白的调节和功能。本综述重点关注胰腺热休克蛋白诱导的现有知识、急性胰腺炎期间热休克蛋白水平的变化、热休克蛋白预诱导和共诱导在实验性急性胰腺炎中的潜在作用，以及热休克蛋白介导细胞保护的机制。
