Lamberts S W, Birkenhäger J C
J Clin Endocrinol Metab. 1976 May;42(5):864-8. doi: 10.1210/jcem-42-5-864.
Lean body mass and body fat mass were estimated in 12 patients with Cushing's disease before treatment, in 5 of these after correction of the adrenal hyperfunction, and in 23 patients with simple obesity. The methods used, whole-body counting of 40K and tritiated water dilution, may in Cushing's disease over- and underestimate, respectively, the body fat mass and may therefore be considered to give upper and lower limits of that entity. By a comparison with the results in simple obesity, we conclude that the total body fat mass generally is increased in patients with Cushing's disease.
对12例库欣病患者在治疗前、其中5例肾上腺功能亢进得到纠正后以及23例单纯性肥胖患者进行了去脂体重和体脂量评估。所采用的方法，即全身40K计数法和氚水稀释法，在库欣病中可能分别高估和低估体脂量，因此可认为给出了该指标的上限和下限。通过与单纯性肥胖患者的结果进行比较，我们得出结论，库欣病患者的总体脂量通常会增加。
