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膀胱肿瘤的长期监测:英国和爱尔兰的当前实践

Long-term surveillance of bladder tumours: current practice in the United Kingdom and Ireland.

作者信息

Wazait H D, Al-Bhueissi S Z, Patel H R H, Nathan M S, Miller R A

机构信息

Department of Urology, Whittington Hospital NHS Trust, Jenner Building, Highgate Hill, London N19 5NF, UK.

出版信息

Eur Urol. 2003 May;43(5):485-8; discussion 488. doi: 10.1016/s0302-2838(03)00052-6.

Abstract

INTRODUCTION

Surveillance of transitional cell carcinoma of the bladder forms a major part of the workload of many urology units. Unfortunately, the policy for long-term surveillance of these cancers is neither clear nor agreed upon in the absence of evidence base. Our study was performed to provide current national practice data, and begin the debate on consensus guidelines.

MATERIALS AND METHODS

A questionnaire was sent to Consultant Urologists (CUs) in the UK and Ireland (n=501) asking about their policy on the long-term surveillance of different bladder tumours once patients are free of recurrence.

RESULTS

A 73% response rate was observed (365/501). Views varied considerably. They ranged from life long cystoscopic surveillance for low-stage low-grade tumours (pTaG1) to discharge after 5 years (or less) of a recurrence-free period for pT1G3 tumour. Once long-term surveillance with cystoscopy had been discontinued, 55% of CUs felt no role was indicated for urine cytology in further follow up, whereas 17% would use it for all tumour types and 28% are selective.

CONCLUSION

Our study has shown the complete lack of consensus regarding the long-term surveillance of bladder cancer in the UK and Ireland. This has major implications for policy making, resources allocation and cancer survival. We highlight the need for national guidelines in this area for optimal surveillance of bladder cancer, as a good prospective evidence-based data will not be available for many years. We believe our study might form the basis for discussion on such guidelines.

摘要

引言

膀胱移行细胞癌的监测是许多泌尿外科单位工作量的主要组成部分。不幸的是,在缺乏循证依据的情况下,这些癌症的长期监测政策既不明确,也未达成共识。我们开展这项研究是为了提供当前的全国实践数据,并开启关于共识指南的讨论。

材料与方法

向英国和爱尔兰的泌尿外科顾问医生(CUs)(n = 501)发送了一份问卷,询问他们对于患者无复发后不同膀胱肿瘤长期监测的政策。

结果

观察到回复率为73%(365/501)。观点差异很大。从对低分期低级别肿瘤(pTaG1)进行终身膀胱镜监测,到pT1G3肿瘤在无复发期5年(或更短时间)后予以出院。一旦停止膀胱镜长期监测,55%的泌尿外科顾问医生认为进一步随访中尿细胞学检查无作用,而17%会对所有肿瘤类型都使用尿细胞学检查,28%则有选择地使用。

结论

我们的研究表明,英国和爱尔兰在膀胱癌长期监测方面完全缺乏共识。这对政策制定、资源分配和癌症生存率有重大影响。我们强调在这一领域需要国家指南以实现膀胱癌的最佳监测,因为多年内都无法获得良好的前瞻性循证数据。我们相信我们的研究可能为此类指南的讨论奠定基础。

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