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免疫功能正常宿主的原发性皮肤毛霉病:一例报告

Primary cutaneous mucormycosis in an immunocompetent host: report of a case.

作者信息

Kumar Arvind, Khilnani Gopi C, Aggarwal Sandeep, Kumar Subodh, Banerjee Uma, Xess Immaculata

机构信息

Department of Surgical Disciplines, All India Institute of Medical Sciences, New Dehli, India.

出版信息

Surg Today. 2003;33(4):319-22. doi: 10.1007/s005950300073.

Abstract

Cutaneous mucormycosis is an uncommon disease and it usually affects immunocompromised, diabetic, and trauma patients with contaminated wounds or patients with underlying malignancies. It is very rare to find this disease in immunocompetent, nondiabetic patients. We herein report a case of primary cutaneous mucormycosis in an immunocompetent and nondiabetic patient. Our patient was a 50-year-old veterinary doctor. He was diagnosed to have cutaneous mucormycosis of the anterior abdominal wall, and was treated with multiple debridements of the wound and intravenous amphotericin B therapy. He received a total of 1000 mg of amphotericin B. A high index of clinical suspicion and early institution of therapy in the form of surgical debridements and antifungal drugs are required to achieve a successful outcome.

摘要

皮肤毛霉病是一种罕见疾病,通常影响免疫功能低下、糖尿病以及伤口受污染的创伤患者或患有潜在恶性肿瘤的患者。在免疫功能正常的非糖尿病患者中发现这种疾病非常罕见。我们在此报告一例免疫功能正常的非糖尿病患者发生原发性皮肤毛霉病的病例。我们的患者是一名50岁的兽医。他被诊断患有前腹壁皮肤毛霉病,并接受了多次伤口清创和静脉注射两性霉素B治疗。他总共接受了1000毫克的两性霉素B。为了取得成功的治疗效果,需要高度的临床怀疑,并以手术清创和抗真菌药物的形式尽早开始治疗。

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