Nain Prabhdeep Singh, Matta Harish, Singh Kuldip, Chhina Deepinder, Trehan Munish, Batta Nishant
Department of Surgery, Dayanand Medical College & Hospital, Ludhiana, Punjab 141001 India.
Indian J Surg. 2015 Dec;77(Suppl 2):253-6. doi: 10.1007/s12262-012-0786-z. Epub 2012 Dec 7.
Mucormycosis is caused by saprophtytic fungi which cause acute invasive zygomycosis. It clinically presents with necrosis, and on histopathology, acute and chronic infiltrates are seen. It rarely infects a healthy host, but is devastating in an immunocompromised host. We studied five cases with post-operative abdominal wall mucormycosis, three females and two males. Three patients were post-operative while the other two had mucormycosis following trauma and infection was found in sutured wound. All were initially diagnosed as cases of necrotizing fasciitis. Two patients eventually survived after intensive medical therapy and extensive debridements.
毛霉病由腐生真菌引起,可导致急性侵袭性接合菌病。临床上表现为坏死,组织病理学可见急性和慢性浸润。它很少感染健康宿主,但在免疫功能低下的宿主中具有毁灭性。我们研究了5例术后腹壁毛霉病患者,其中3例女性,2例男性。3例患者为术后发病,另外2例在创伤后发生毛霉病,感染出现在缝合伤口处。所有患者最初均被诊断为坏死性筋膜炎。2例患者经过强化药物治疗和广泛清创后最终存活。