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[乳腺癌Ⅰ期和Ⅱ期传播研究中的成本效益]

[Cost-benefit in the study of the dissemination of stage I and II in breast cancer].

作者信息

Camacho Jamile, Barriga Carolina, Escobar Paula, Seleme Nicolás, Schwartz Rodrigo

机构信息

Departamento de Cirugía Oriente, Facultad de Medicina, Universidad de Chile, Servicio de Cirugía, Hospital del Salvador.

出版信息

Rev Med Chil. 2003 Feb;131(2):155-7.

Abstract

BACKGROUND

Chest X ray, abdominal ultrasound and bone scintigraphy are usually requested to study a possible dissemination of breast carcinoma.

AIM

To study the yield and costs of these exams in the study of dissemination of stage I and II breast carcinoma.

MATERIAL AND METHODS

A retrospective analysis of patients operated for a breast carcinoma in a public surgical service. A chest X ray, abdominal ultrasound and bone scintigraphy was requested to all patients in the immediate postoperative period. Age, stage according to pathological TNM and costs per patient were registered.

RESULTS

Of 210 women operated, 40 were in stage I (19%) and 85 in stage II (41%). Dissemination study was negative in all stage I patients and in all but two patients in stage II. The yield for detection of distant metastases in these patients was 0.9% for chest X ray, 0% for abdominal ultrasound and 0.9% for bone scintigraphy. The total cost of the study, in Chilean pesos, was $10,369,620 in a public hospital and $16,535,400 in a private clinic.

DISCUSSION

Additional exams to detect distant metastases in early stages of breast carcinoma have a low yield and high costs.

摘要

背景

通常会要求进行胸部X光、腹部超声和骨闪烁扫描来研究乳腺癌可能的扩散情况。

目的

研究这些检查在I期和II期乳腺癌扩散研究中的检出率及成本。

材料与方法

对一家公共外科服务机构中接受乳腺癌手术的患者进行回顾性分析。在术后即刻对所有患者进行胸部X光、腹部超声和骨闪烁扫描。记录患者年龄、根据病理TNM分期以及每位患者的成本。

结果

在接受手术的210名女性中,40名处于I期(19%),85名处于II期(41%)。所有I期患者以及除两名患者外的所有II期患者的扩散研究结果均为阴性。这些患者中,胸部X光检测远处转移的检出率为0.9%,腹部超声为0%,骨闪烁扫描为0.9%。在智利比索计价下,该研究在公立医院的总成本为10369620美元,在私立诊所为16535400美元。

讨论

用于检测早期乳腺癌远处转移的额外检查检出率低且成本高。

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