Testing the effects of fluids on rat skin using disposable polypropylene chambers.

Inexpensive, disposable polypropylene chambers for testing fluids on rat skin were made by removing the wings from polypropylene wing nuts and by cutting into the top of each nut a seat for an O-ring. Polypropylene screws with black heads were fabricated as seals for the chambers. After attachment to the backs of rats, these chambers provided a satisfactory means of keeping fluid in contact with the skin for 3 days.