Bakker H R, Waring H
J Endocrinol. 1976 Apr;69(1):149-57. doi: 10.1677/joe.0.0690149.
A new method is described for placing lesions in the supraoptico-neurohypophysial tract to produce diabetes insipidus. The method is particularly useful with species such as Macropus eugenii in which different individuals show a large variation in relative skull measurements. The development of the diabetes insipidus syndrome in the tammar wallaby (Macropus eugenii) is shown to have essentially the same triphasic pattern of urine production as in eutherians. Increased values of adrenal corticosteroids (less than 16 mug/100 ml plasma) were observed in the oliguric interphase. This has not been previously reported and we suggest that these increased values are most probably due to potentiation of corticotrophic releasing factor by the uncontrolled release of vasopressin during this phase.
描述了一种在视上核-神经垂体束中制造损伤以产生尿崩症的新方法。该方法对于诸如尤金袋鼠（Macropus eugenii）等物种特别有用，在这些物种中，不同个体的相对颅骨测量值存在很大差异。已表明，短尾矮袋鼠（Macropus eugenii）中尿崩症综合征的发展与真兽类动物的尿液生成基本具有相同的三相模式。在少尿间期观察到肾上腺皮质类固醇值升高（低于16微克/100毫升血浆）。此前未报道过这一现象，我们认为这些升高的值很可能是由于在此阶段抗利尿激素不受控制地释放增强了促肾上腺皮质激素释放因子。
