Msika S
Service de Chirurgie Générale et Digestive, Hôpital Louis Mourier--Colombes.
J Chir (Paris). 2003 Feb;140(1):4-21.
The frequency of bariatric surgery has increased markedly in France in recent years, partly due to a better appreciation of the problem of morbid obesity but also due to the commercial introduction of adjustable gastric banding devices which can be placed by laparoscopic approach. Numerous complications of this surgery are known and require recognition to be appropriately treated. Studies of complications suffer from selection bias, methodologic flaws, and lack of follow-up. The incidence and type of complication are affected by the learning curve and surgical techniques. Postoperative mortality varies from 0.14% for laparoscopic gastric banding (LGB), to 0.31% for vertical banded gastroplasty (VBGP) and 0.35% for Roux-en-Y gastric bypass (GBP); pulmonary embolus accounts for 60-70% of deaths in all groups combined. Early post-operative complications vary with specific procedures. Abdominal wall complications, already frequent in an obese population, are decreased from 10% for open procedures to 6% for laparoscopic gastric banding. Both VBGP and GBP are now being done laparoscopically with increasing frequency. Complications specific to LGB include gastric perforation (0.3%), or port problems (5%). Complications with VBGP and GBP include fistula (1-3%), deep abscess, and pulmonary embolus (2%). Global early morbidity is 4.2% for LGB, and varies from 6.4%-22% for VBGP and 6.2%-11.3% for GBP depending on laparoscopic versus open approach. Late mechanical complications are also specific to type of surgery. Pouch dilatation is the most common late complication of LGB (6.3%) and seems related both to operative experience and to site of placement of the band; it has decreased with higher positioning of the band to leave a minimal gastric pouch and with dissection through the pars flaccida of the lesser omentum instead of directly along the muscular wall of the stomach. It usually requires reintervention. Erosion of the gastric band into the stomach (1.6%) is often asymptomatic and is suggested by late weight gain. With VBGP, disruption of a gastric staple line occurs in 12.1% and stenosis of the outlet with proximal dilatation in 6.5%; erosion of the calibrating band of Marlex or silastic occurs in 2.7%. With GBP, the disruption of a staple line across an intact stomach (23%) has become less of a problem with division of the gastric pouch from the distal stomach (2%). Stenosis of the gastrojejunostomy (3.7%) and marginal ulcer (3.5%) are not uncommon. The incidence of wound hernia, obstructive adhesions, and late cholecystectomy vary with the length and thoroughness of follow-up. Late functional complications such as vomiting, dysphagia, heartburn and esophagitis vary with the quality and length of follow-up study. GBP may cause diarrhea and dumping syndrome. Nutritional complications are more common with GPB than with purely restrictive procedures; iron, folate, and Vitamin B12 deficiency are the rule with GBP and require routine replacement therapy; iron deficiency has been noted even with LGB. ate death seems more related to co-morbidities than to the intervention itself. Thorough long-term follow-up study of complications is indispensable for assessment of outcomes and improvement of laparoscopic techniques. Even the less traumatic surgical approach of laparoscopic band placement should not be considered free of risk; strict adherence to pre-operative surgical indications should be maintained.
近年来,减肥手术在法国的实施频率显著增加,部分原因是对病态肥胖问题有了更深入的认识,也因为可通过腹腔镜置入的可调节胃束带装置在商业上的推广。这种手术的众多并发症已为人所知,需要识别出来以便进行恰当治疗。关于并发症的研究存在选择偏倚、方法学缺陷以及缺乏随访等问题。并发症的发生率和类型受学习曲线和手术技术的影响。术后死亡率因手术方式而异,腹腔镜胃束带术(LGB)为0.14%,垂直带状胃成形术(VBGP)为0.31%,Roux-en-Y胃旁路术(GBP)为0.35%;肺栓塞在所有组的死亡病例中占60 - 70%。术后早期并发症因具体手术方式而异。腹壁并发症在肥胖人群中本来就很常见,从开放手术的10%降至腹腔镜胃束带术的6%。VBGP和GBP现在越来越多地通过腹腔镜进行。LGB特有的并发症包括胃穿孔(0.3%)或端口问题(5%)。VBGP和GBP的并发症包括瘘管(1 - 3%)、深部脓肿和肺栓塞(2%)。LGB的总体早期发病率为4.2%,VBGP的早期发病率根据腹腔镜与开放手术方式不同在6.4% - 22%之间,GBP的早期发病率在6.2% - 11.3%之间。晚期机械性并发症也因手术类型而异。胃囊扩张是LGB最常见的晚期并发症(6.3%),似乎与手术经验和束带放置位置有关;随着束带位置升高以保留最小胃囊以及通过小网膜的松弛部而非直接沿着胃肌壁进行分离,其发生率有所下降。通常需要再次干预。胃束带侵蚀入胃(1.6%)通常无症状,后期体重增加提示可能发生这种情况。对于VBGP,胃吻合钉线破裂发生率为12.1%,出口狭窄伴近端扩张发生率为6.5%;Marlex或硅橡胶校准带侵蚀发生率为2.7%。对于GBP,完整胃上吻合钉线破裂(23%)随着胃囊与远端胃分离(2%)已不再是大问题。胃空肠吻合口狭窄(3.7%)和边缘溃疡(3.5%)并不少见。伤口疝、梗阻性粘连和晚期胆囊切除术的发生率因随访时间长短和全面程度而异。晚期功能性并发症如呕吐、吞咽困难、烧心和食管炎因随访研究的质量和时间长短而异。GBP可能导致腹泻和倾倒综合征。营养并发症在GBP中比单纯限制性手术更常见;GBP通常会出现铁、叶酸和维生素B12缺乏,需要常规替代治疗;即使是LGB也有缺铁的情况。晚期死亡似乎更多与合并症有关而非手术本身。对并发症进行全面的长期随访研究对于评估手术效果和改进腹腔镜技术必不可少。即使是创伤较小的腹腔镜束带置入手术方式也不应被视为无风险;应严格遵守术前手术指征。