Straznicky K
J Embryol Exp Morphol. 1976 Feb;35(1):41-57.
The retinotectal connexions of double nasal (NN), double temporal (TT) and double ventral (VV) eyes in juvenile Xenopus were mapped after post-metamorphic removal of the rostral, caudal, medial or lateral tectal halves with the subsequent cutting of the optic nerve of the operated eye. A whole visual field projection occurred from NN eyes on to residual caudal tectum, from TT eyes on to residual rostral tectum and from VV eyes on to residual medial tectum. When optic fibres from NN, TT or VV eyes grew into inappropriate rostral, caudal or lateral tectal halves respectively, there was a projection deficit in the nasal and temporal or in the dorsal and ventral poles of the visual field. The persisting scotomas in the visual field indicated that only the optic fibres of the central retinal fundus had succeeded in connecting with an inappropriate tectal half whereas the peripheral optic fibres had not. The incongruous results of optic nerve regeneration obtained in the various recombinations may be taken to indicate that the assumption of early embryonic pattern regulation is inadequate to explain the findings in this experimental situation.
在非洲爪蟾幼体变态后，分别切除前脑、后脑、中脑或外侧脑的一半，随后切断手术眼的视神经，绘制了双鼻（NN）、双颞（TT）和双腹（VV）眼的视网膜 - 脑顶盖连接图谱。NN眼向残留的后脑顶盖投射整个视野，TT眼向残留的前脑顶盖投射，VV眼向残留的中脑顶盖投射。当来自NN、TT或VV眼的视神经纤维分别长入不适当的前脑、后脑或外侧脑半叶时，视野的鼻侧和颞侧或背侧和腹侧极会出现投射缺陷。视野中持续存在的暗点表明，只有视网膜中央眼底的视神经纤维成功与不适当的脑顶盖半叶相连，而周边视神经纤维则没有。在各种重组中获得的视神经再生的不一致结果可能表明，早期胚胎模式调节的假设不足以解释这种实验情况下的结果。
