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[颈椎嗜酸性肉芽肿:病例报告]

[Eosinophilic granuloma of the cervical spine: case report].

作者信息

Leal Filho Manoel Baldoino, Aguiar Aline de Almeida Xavier, de Almeida Bruno Ribeiro, Dantas Karoline da Silva, Vieira Marcelo Adriano da Cunha e Silva, de Morais Ricardo Keyson Paiva

机构信息

Hospital Getúlio Vargas e Universidade Federal do Piaui, Teresina, Brasil.

出版信息

Arq Neuropsiquiatr. 2003 Mar;61(1):141-3. doi: 10.1590/s0004-282x2003000100030. Epub 2003 Apr 16.

Abstract

Eosinophilic granuloma (EG) is a benign condition of histocytes proliferation localized or multifocal. It is presents in the cervical spine in 1.5%-20% of the cases of EG. We report the case of a seven-year-old girl that presented with a one month history of cervical pain, persistent wryneck and vicious posture of the neck. A computerized tomography was performed and confirmed the presence of spreading lesion, ostheodestructive to the level of the left laminae of C2, with invasion of the spine and the muscular tissue. A laminectomy was underwent for removal of the lesion. The patient had a good post-operative recovery with improvement of the symptoms. Chemotherapy with prednisone, vinblastine and ethoposide was administred. After six months, this protocol was repeated associaded to methotrexate. The patient improved and had no new symptoms in a follow-up of 36 months.

摘要

嗜酸性肉芽肿(EG)是一种组织细胞增殖的良性疾病,可为局限性或多灶性。在EG病例中,1.5% - 20%会出现在颈椎。我们报告一例七岁女孩,有一个月的颈部疼痛、持续性斜颈和颈部不良姿势病史。进行了计算机断层扫描,证实存在扩散性病变,对C2左侧椎板水平有骨质破坏,并侵犯了脊柱和肌肉组织。为切除病变进行了椎板切除术。患者术后恢复良好,症状有所改善。给予泼尼松、长春碱和依托泊苷进行化疗。六个月后,重复该方案并联合甲氨蝶呤。患者病情改善,在36个月的随访中没有出现新症状。

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