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将多发性骨髓瘤的反应标准应用于华氏巨球蛋白血症是否合适?

Appropriateness of applying the response criteria for multiple myeloma to Waldenstrom's macroglobulinemia?

作者信息

Bladé Joan, Montoto Silvia, Rosiñol Laura, Montserrat Emili

机构信息

Department of Hematology, Institute of Hematology and Oncology, Postgraduate School of Hematology Farreras Valentí, Hospital Clínic, University of Barcelona, Barcelona, Spain.

出版信息

Semin Oncol. 2003 Apr;30(2):329-31. doi: 10.1053/sonc.2003.50055.

Abstract

Since the presence of an M-component is an essential disease feature in both multiple myeloma (MM) and Waldenstrom's macroglobulinemia (WM), the decrease in the M-protein size applied for response in MM is also a crucial criteria for assessing response in WM. However, WM frequently displays lymphoma-like features that should be included in the response criteria.

摘要

由于M蛋白成分的存在是多发性骨髓瘤(MM)和华氏巨球蛋白血症(WM)的基本疾病特征,因此MM中用于评估缓解的M蛋白大小的降低也是评估WM缓解情况的关键标准。然而,WM常表现出淋巴瘤样特征,这些特征应纳入缓解标准中。

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