Bino Silvia, Kakarriqi Eduard, Xibinaku Miriam, Ion-Nedelcu Nicolae, Bukli Mariana, Emiroglu Nedret, Uzicanin Amra
Institute of Public Health, Tirana, Albania.
J Infect Dis. 2003 May 15;187 Suppl 1:S223-9. doi: 10.1086/368055.
In 2000, Albania resolved to eliminate measles by 2007 by use of a four-step program: by conducting a "catch-up" vaccination campaign for all children aged 1-14 years, achieving and sustaining high coverage (>/=95%) among children aged 1 year with the first dose of a measles-containing vaccine, by introducing a routine second dose of measles-containing vaccine for children at age 5 years, and by improving measles surveillance. This catch-up campaign took place in November 2000: 867,000 doses of measles-rubella vaccine were administered for an estimated coverage of 99%. In all, 231 campaign-related adverse events were reported: syncope, 206; allergic reactions, 10; fever, 8; encephalitis/encephalopathy, 2; and aseptic meningitis, seizures, Guillain-Barré syndrome, anaphylaxis, and arthralgia, 1 each. All resolved without sequelae. This report describes the status of measles and rubella/congenital rubella syndrome control in Albania before 2000 and reports on implementation of the catch-up campaign.
2000年,阿尔巴尼亚决定通过一项四步计划在2007年前消除麻疹:为所有1至14岁儿童开展“强化免疫”疫苗接种活动;在1岁儿童中实现并维持含麻疹疫苗首剂的高接种率(≥95%);为5岁儿童引入含麻疹疫苗的常规第二剂接种;以及改善麻疹监测。此次强化免疫活动于2000年11月开展:共接种86.7万剂麻疹风疹疫苗,估计接种率达99%。总共报告了231起与活动相关的不良事件:晕厥206例;过敏反应10例;发热8例;脑炎/脑病2例;无菌性脑膜炎、癫痫、格林-巴利综合征、过敏反应和关节痛各1例。所有病例均康复且无后遗症。本报告描述了2000年前阿尔巴尼亚麻疹和风疹/先天性风疹综合征的控制状况,并报告了强化免疫活动的实施情况。