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大规模麻疹风疹免疫运动:不丹的经验

Mass measles rubella immunization campaign: bhutan experience.

作者信息

Giri Bhakta R, Namgyal Pem, Tshering Kp, Sharma Kp, Dorji Tandin, Tamang Chewang

机构信息

Department of Internal Medicine, Royal Rattanak Hospital, Phnom Penh, Cambodia.

出版信息

Indian J Community Med. 2011 Apr;36(2):109-13. doi: 10.4103/0970-0218.84128.

DOI:10.4103/0970-0218.84128
PMID:21976794
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3180934/
Abstract

BACKGROUND

Bhutan has attained universal child immunization since 1991. Since then, immunization coverage is maintained at high level through routine immunization, periodic National Immunization Days, and mop up campaigns. Despite high immunization coverage, every year, significant numbers of clinically suspected measles cases were reported.

OBJECTIVE

To assess the cause of continuing high "suspected measles cases" and take appropriate public health measures.

MATERIALS AND METHODS

Febrile rash outbreaks occurred in several districts in 2003. These episodes were investigated. Simultaneously, a retrospective data search revealed evidence of congenital rubella syndrome (CRS) in the country.

RESULTS

Thirty five percent of the tested samples were positive for rubella but none for measles. There were evidences of the presence of CRS. This was discussed in the annual health conference 2004, amongst health policy makers and district heads who recommended that a possibility of inclusion of rubella as an antigen be looked into. A nationwide measles and rubella immunization campaign was conducted in 2006 followed by introduction of rubella vaccine in the immunization schedule.

CONCLUSION

Febrile rash can be caused by a host of viral infections. Following universal measles immunization, it is pertinent that febrile rash be looked in the light of rubella infections. Following the introduction of rubella vaccination in the national immunization schedule, there has been significant reduction of febrile rash episodes, cases of rubella, and congenital rubella syndrome.

摘要

背景

不丹自1991年起实现了儿童免疫接种全覆盖。自那时起,通过常规免疫接种、定期的全国免疫日活动及查漏补种活动,免疫接种覆盖率一直维持在较高水平。尽管免疫接种覆盖率很高,但每年仍有大量临床疑似麻疹病例报告。

目的

评估持续出现大量“疑似麻疹病例”的原因并采取适当的公共卫生措施。

材料与方法

2003年,几个地区发生了发热出疹疫情。对这些疫情进行了调查。同时,一项回顾性数据检索发现该国存在先天性风疹综合征(CRS)的证据。

结果

35%的检测样本风疹呈阳性,但麻疹均为阴性。有证据表明存在先天性风疹综合征。在2004年的年度卫生会议上,卫生政策制定者和地区负责人对此进行了讨论,他们建议研究将风疹作为一种抗原纳入免疫规划的可能性。2006年开展了全国性的麻疹和风疹免疫接种活动,随后在免疫规划中引入了风疹疫苗。

结论

发热出疹可能由多种病毒感染引起。在实现麻疹普遍免疫接种后,鉴于风疹感染,对发热出疹进行排查很有必要。在国家免疫规划中引入风疹疫苗后,发热出疹疫情、风疹病例及先天性风疹综合征病例显著减少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/3180934/787e27cfc1ff/IJCM-36-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/3180934/2cdd0885a0ae/IJCM-36-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/3180934/787e27cfc1ff/IJCM-36-109-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/3180934/2cdd0885a0ae/IJCM-36-109-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/baca/3180934/787e27cfc1ff/IJCM-36-109-g002.jpg

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Mass measles immunization campaign: experience in the Hong Kong Special Administrative Region of China.大规模麻疹免疫运动:中国香港特别行政区的经验
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