Cardan E, Micluţia M, Imre S
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1975 May-Jun;24(3):223-8.
The authors made an experimental investigation in the dog concerning the evolution of the muscular clearance of phenoxybenzamine in the course of de-shocking procedures. The animals were shocked by hemorrhage and were treated by perfusion of volemic mass and administration of phenoxybenzamine. This substance was flowed in paralell with the hemodynamic parameters and the rhythm of the diuresis. It was noted that the direction and the amplitude of changes concerning the half-life of Na131I do not depend on the blood pressure.
作者对狗进行了一项实验研究,以探讨在抗休克过程中酚苄明肌肉清除率的变化情况。通过出血使动物休克,并通过输注血容量物质和给予酚苄明进行治疗。该物质与血流动力学参数和利尿节律平行流动。结果发现,关于Na131I半衰期的变化方向和幅度并不取决于血压。